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Recombinant Human USP8 Protein, Myc/DDK-tagged, C13 and N15-labeled

Cat.No. : USP8-3738H
Product Overview : USP8 MS Standard C13 and N15-labeled recombinant protein (NP_005145) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.
  • Specification
  • Gene Information
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Description : This gene encodes a protein that belongs to the ubiquitin-specific processing protease family of proteins. The encoded protein is thought to regulate the morphology of the endosome by ubiquitination of proteins on this organelle and is involved in cargo sorting and membrane trafficking at the early endosome stage. This protein is required for the cell to enter the S phase of the cell cycle and also functions as a positive regulator in the Hedgehog signaling pathway in development. Pseudogenes of this gene are present on chromosomes 2 and 6. Alternate splicing results in multiple transcript variants.
Source : HEK293
Species : Human
Tag : Myc/DDK
Molecular Mass : 127.3 kDa
AA Sequence : MPAVASVPKELYLSSSLKDLNKKTE VKPEKISTKSYVHSALKIFKTAEEC RLDRDEERAYVLYMKYVTVYNLIKK RPDFKQQQDYFHSILGPGNIKKAVE EAERLSESLKLRYEEAEVRKKLEEK DRQEEAQRLQQKRQETGREDGGTLA KGSLENVLDSKDKTQKSNGEKNEKC ETKEKGAITAKELYTMMTDKNISLI IMDARRMQDYQDSCILHSLSVPEEA ISPGVTASWIEAHLPDDSKDTWKKR GNVEYVVLLDWFSSAKDLQIGTTLR SLKDALFKWESKTVLRNEPLVLEGG YENWLLCYPQYTTNAKVTPPPRRQN EEVSISLDFTYPSLEESIPSKPAAQ TPPASIEVDENIELISGQNERMGPL NISTPVEPVAASKSDVSPIIQPVPS IKNVPQIDRTKKPAVKLPEEHRIKS ESTNHEQQSPQSGKVIPDRSTKPVV FSPTLMLTDEEKARIHAETALLMEK NKQEKELRERQQEEQKEKLRKEEQE QKAKKKQEAEENEITEKQQKAKEEM EKKESEQAKKEDKETSAKRGKEITG VKRQSKSEHETSDAKKSVEDRGKRC PTPEIQKKSTGDVPHTSVTGDSGSG KPFKIKGQPESGILRTGTFREDTDD TERNKAQREPLTRARSEEMGRIVPG LPSGWAKFLDPITGTFRYYHSPTNT VHMYPPEMAPSSAPPSTPPTHKAKP QIPAERDREPSKLKRSYSSPDITQA IQEEEKRKPTVTPTVNRENKPTCYP KAEISRLSASQIRNLNPVFGGSGPA LTGLRNLGNTCYMNSILQCLCNAPH LADYFNRNCYQDDINRSNLLGHKGE VAEEFGIIMKALWTGQYRYISPKDF KITIGKINDQFAGYSQQDSQELLLF LMDGLHEDLNKADNRKRYKEENNDH LDDFKAAEHAWQKHKQLNESIIVAL FQGQFKSTVQCLTCHKKSRTFEAFM YLSLPLASTSKCTLQDCLRLFSKEE KLTDNNRFYCSHCRARRDSLKKIEI WKLPPVLLVHLKRFSYDGRWKQKLQ TSVDFPLENLDLSQYVIGPKNNLKK YNLFSVSNHYGGLDGGHYTAYCKNA ARQRWFKFDDHEVSDISVSSVKSSA AYILFYTSLGPRVTDVATTRTRPLE QKLISEEDLAANDILDYKDDDDKV
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Stability : Stable for 3 months from receipt of products under proper storage and handling conditions.
Storage : Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
Concentration : 50 μg/mL as determined by BCA
Storage Buffer : 100 mM glycine, 25 mM Tris-HCl, pH 7.3.
Gene Name : USP8 ubiquitin specific peptidase 8 [ Homo sapiens (human) ]
Official Symbol : USP8
Synonyms : USP8; ubiquitin specific peptidase 8; ubiquitin specific protease 8; ubiquitin carboxyl-terminal hydrolase 8; HumORF8; KIAA0055; UBPY; hUBPy; ubiquitin isopeptidase Y; ubiquitin thioesterase 8; deubiquitinating enzyme 8; ubiquitin thiolesterase 8; ubiquitin-specific-processing protease 8; FLJ34456; MGC129718;
Gene ID : 9101
mRNA Refseq : NM_005154
Protein Refseq : NP_005145
MIM : 603158
UniProt ID : P40818

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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