VEGFB

  • Official Full Name

    vascular endothelial growth factor B

  • Overview

    This gene encodes a member of the PDGF (platelet-derived growth factor)/VEGF (vascular endothelial growth factor) family. The VEGF family members regulate the formation of blood vessels and are involved in endothelial cell physiology. This member is a ligand for VEGFR-1 (vascular endothelial growth factor receptor 1) and NRP-1 (neuropilin-1). Studies in mice showed that this gene was co-expressed with nuclear-encoded mitochondrial genes and the encoded protein specifically controlled endothelial uptake of fatty acids. Alternatively spliced transcript variants encoding distinct isoforms have been identified.
  • Synonyms

    VEGFB; vascular endothelial growth factor B; VEGF-related factor; Vrf; VEGF-B;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Cattle
  • Dog
  • Human
  • Mouse
  • Rat
  • E.coli
  • HEK293
  • HEK293T
  • Human
  • Human Cell
  • Mammalian cell
  • Mammalian Cell
  • Yeast
  • C
  • His
  • hFc
  • His (Fc)
  • Avi
  • Strep
  • His|T7
  • GST
  • Myc
  • DDK
  • N/A
  • N
  • No tag
  • Strep II
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human VEGFB-202H Active Recombinant Human VEGFB E.coli N/A
Human VEGFB-554H Recombinant Human VEGFB, His-tagged Human His
Human VEGFB-640H Recombinant Human Vascular Endothelial Growth Factor B Human N/A
Human VEGFB-275H Active Recombinant Human VEGFB protein, hFc-tagged HEK293 hFc Pro22-Ala207
Human VEGFB-17H Active Recombinant Human VEGFB protein, His-tagged HEK293 His Pro 22 - Ala 207
Human VEGFB-280H Recombinant Human VEGFB, StrepII-tagged Human Cell Strep II 22-207, 186 a.a.
Human VEGFB-128H Recombinant Human Vascular Endothelial Growth Factor B, His-tagged E.coli His
Human VEGFB-598H Recombinant Human VEGFB protein, His & T7-tagged E.coli His/T7 Pro22~Ala207 (Accession # P49765)
Human VEGFB-416HCL Recombinant Human VEGFB 293 Cell Lysate HEK293 N/A
Human VEGFB-1554H Recombinant Human VEGFB Protein (22-207 aa), His-tagged Yeast His 22-207 aa
Human VEGFB-1428H Recombinant Human VEGFB protein, His-GST & Myc-tagged E.coli His-GST & Myc 22-207aa
Human VEGFB-1952H Recombinant Human VEGFB Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human VEGFB-0505H Recombinant Human VEGFB Protein (M1-A207), His/Strep tagged Mammalian cell His/Strep M1-A207
Human VEGFB-107H Active Recombinant Human VEGFB Protein E.coli
Human VEGFB-0506H Recombinant Human VEGFB Protein (M1-A207), Tag Free Mammalian cell No tag M1-A207
Human VEGFB-6558H Recombinant Human VEGFB Protein (Pro22-Ala207), N-His tagged E.coli N-His Pro22-Ala207
Human VEGFB-6557H Recombinant Human VEGFB Protein (Pro22-Arg188), C-His tagged E.coli C-His Pro22-Arg188
Mouse Vegfb-254M Active Recombinant Mouse Vegfb E.coli N/A
Mouse Vegfb-599M Recombinant Mouse Vegfb protein, His & T7-tagged E.coli His/T7 Ala21~Ala207 (Accession # P49766)
Mouse VEGFB-18005M Recombinant Mouse VEGFB Protein Mammalian Cell His
Mouse VEGFB-10008M Recombinant Mouse VEGFB Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse VEGFB-10008M-B Recombinant Mouse VEGFB Protein Pre-coupled Magnetic Beads HEK293
Rat Vegfb-600R Recombinant Rat Vegfb protein, His-tagged E.coli His Ala21~Ser137
Rat VEGFB-6514R Recombinant Rat VEGFB Protein Mammalian Cell His
Rat VEGFB-6170R Recombinant Rat VEGFB Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat VEGFB-6170R-B Recombinant Rat VEGFB Protein Pre-coupled Magnetic Beads HEK293
Dog VEGFB-597D Recombinant Dog VEGFB protein, His & T7-tagged E.coli His/T7 Pro22~Arg137 (Accession # E2R9R3)
Cattle VEGFB-596C Recombinant Cattle VEGFB protein, His & T7-tagged E.coli His/T7 Pro22~Ser137 (Accession # Q9XS49)
Cattle VEGFB-565C Recombinant Cattle VEGFB Protein, His-tagged E.coli N-His Pro22-Arg188
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • Other Resource

VEGFB involved in several pathways and played different roles in them. We selected most pathways VEGFB participated on our site, such as Ras signaling pathway, Rap signaling pathway, Cytokine-cytokine receptor interaction, which may be useful for your reference. Also, other proteins which involved in the same pathway with VEGFB were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Ras signaling pathwayCSF1;RAC3;NGFR;PLA2G12B;GNG8;PDGFD;ANGPT2;Fasl;RGL1
Rap signaling pathwayCALM4;Itgam&Itgb2;PLCB1;CDH1;MAP2K1;GNAI1;TEK;INS1;FPR1
Cytokine-cytokine receptor interactionLTB;IL12A;IL-8;IL11RA;CCL7;CXCL1;BMP2;TNFRSF8;IFNA3
PIK-Akt signaling pathwayFGF21;THBS2;Il2;NGF;PPP2R3C;AKT2;IFNA1;GH1;FGF2
Focal adhesionFLNC;ROCK1;THBS3;PDGFB;LAMA4;LAMB4;RAF1A;PPP1CAA;THBS1
Pathways in cancerVEGFA;NKX3;ITGA2;TRAF3;HRAS;WNT3A;CTBP2;LAMB3;PLD1

VEGFB has several biochemical functions, for example, chemoattractant activity, growth factor activity, heparin binding. Some of the functions are cooperated with other proteins, some of the functions could acted by VEGFB itself. We selected most functions VEGFB had, and list some proteins which have the same functions with VEGFB. You can find most of the proteins on our site.

Function Related Protein
chemoattractant activityVEGFB;VEGFC;FIGF;HMGB1;FGF2;PDGFB;SAA3;BMP4;FGF8
growth factor activityPPBP;SPAW;GDNFA;IL4;KITLG;Fgf15;IL7;IL10;CXCL1
heparin bindingTHBS1;CFH;APOA5;SLIT1A;CCL8;RPL22;SELL;SFRP1;HRG
protein bindingIARS;HIST1H4E;BLMH;GSTM4;PTBP3;SLC9A3R1;CARS;MIS18A;CCDC9
protein heterodimerization activityTIRAP;TTR;NFKB1;HIST1H4K;PPP3CB;HIST2H2AA4;MAFA;ZBTB1;Bcl2a1b
protein homodimerization activitySYT14;NPR3;TARBP2;TESC;QPRT;ATPIF1A;EPHX2;HSP90AA1;NKX2
vascular endothelial growth factor receptor 1 bindingVEGFB;VEGFA

VEGFB has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with VEGFB here. Most of them are supplied by our site. Hope this information will be useful for your research of VEGFB.

VEGFA; ftsK

Research Area

Related articles

Lee, JE; Kim, C; et al. Novel Glycosylated VEGF Decoy Receptor Fusion Protein, VEGF-Grab, Efficiently Suppresses Tumor Angiogenesis and Progression. MOLECULAR CANCER THERAPEUTICS 14:470-479(2015).
Vecchione, A; Belletti, B; et al. A microRNA signature defines chemoresistance in ovarian cancer through modulation of angiogenesis. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 110:9845-9850(2013).
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