Active Recombinant Human VEGFB Protein

• Cat.No.: VEGFB-107H
• Product Overview: The mature recombinant human VEGF-B protein (22-188aa) without tag was expressed in E. coli.

Specification

• Species: Human
• Source: E.coli
• Description: This gene encodes a member of the PDGF (platelet-derived growth factor)/VEGF (vascular endothelial growth factor) family. The VEGF family members regulate the formation of blood vessels and are involved in endothelial cell physiology. This member is a ligand for VEGFR-1 (vascular endothelial growth factor receptor 1) and NRP-1 (neuropilin-1). Studies in mice showed that this gene was co-expressed with nuclear-encoded mitochondrial genes and the encoded protein specifically controlled endothelial uptake of fatty acids. Alternatively spliced transcript variants encoding distinct isoforms have been identified.
• Bio-activity: Measured by its binding ability in a functional ELISA. Immobilized recombinant rat Neuropilin-1 Fc Chimera at 4 μg/mL (100 μL/well) can bind recombinant human VEGF-B with a linear range of 0.3-20 ng/mL.
• Molecular Mass: 19 kDa
• Product-Related Proteins: 22-188
• Storage: At -80 centigrade. Avoid repeated freeze-thaw cycles.
• Storage Buffer: PBS

Gene Information

• Gene Name: VEGFB vascular endothelial growth factor B [ Homo sapiens (human) ]
• Official Symbol: VEGFB
• Synonyms: VEGFB; vascular endothelial growth factor B; VRF; VEGFL; vascular endothelial growth factor B; Names; VEGF-related factor
• Gene ID: 7423
• mRNA Refseq: NM_003377
• Protein Refseq: NP_003368
• MIM: 601398
• UniProt ID: P49765