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XCL1

  • Official Full Name

    chemokine (C motif) ligand 1

  • Overview

    Lymphotactin (LTN); is a chemokine produced mainly by activated CD8+ T-cells and directs migration of CD4+ and CD8+ lymphocytes and natural killer (NK); cells.1 LTN plays an important role in maintaining the integrity of the epithelium and in mucosal immu
  • Synonyms

    XCL1; chemokine (C motif) ligand 1; lymphotactin; lymphotaxin; cytokine SCM-1; c motif chemokine 1; small-inducible cytokine C1; small inducible cytokine subfamily C, member 1 (lymphotactin); LTN; ATAC; Lptn; SCM-1; Scyc1; SCM-1a; AI661682;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Canine
  • Chicken
  • Cynomolgus Monkey
  • Human
  • Mouse
  • Rat
  • Rhesus Macaque
  • CHO
  • E.coli
  • HEK293
  • Insect Cell
  • Mammalian Cell
  • Biotin
  • Fc
  • Fc, mutant
  • His
  • His (Fc)
  • Avi
  • His|Fc
  • His|GST
  • His|S
  • His|T7
  • N/A
  • N
  • GST
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human XCL1-160H Active Recombinant Human XCL1, MIgG2a Fc-tagged CHO Fc
Human XCL1-001H Active Recombinant Human XCL1,HIgG1 Fc-tagged CHO Fc
Human XCL1-159H Active Recombinant Human XCL1, HIgG1 Fc-tagged, mutant CHO Fc, mutant
Human XCL1-06H Recombinant Human XCL1 protein, His/Fc-tagged HEK293 His/Fc Val22-Gly114
Human XCL1-241H Recombinant Human XCL1 Protein, His-tagged Insect Cell His
Human XCL1-05H Recombinant Human XCL1 protein E.coli N/A 92
Human XCL1-158H Recombinant Human Lymphotactin, His-tagged E.coli His
Human XCL1-28843TH Recombinant Human XCL1, His-tagged E.coli His
Human XCL1-27983TH Recombinant Human XCL1 E.coli N/A
Human XCL1-466HCL Recombinant Human XCL1 cell lysate Insect Cell N/A
Human XCL1-6245H Recombinant Human XCL1 Protein (Ser27-Asn107), His tagged E.coli His Ser27-Asn107
Human XCL1-6246H Recombinant Human XCL1 Protein (Val22-Gly114), N-GST tagged E.coli N-GST Val22-Gly114
Human XCL1-85H Recombinant Human XCL1 Protein E.coli 93 amino acid
Human XCL1-88H Recombinant Human XCL1 Protein, Biotin-tagged E.coli Biotin
Human XCL1-084X Active Recombinant Human XCL1 Protein (92 aa) E.coli 92
Mouse Xcl1-234M Recombinant Mouse Xcl1 protein, His/S-tagged E.coli His/S
Mouse Xcl1-637M Recombinant Mouse Xcl1, His tagged Insect Cell His Met 1-Gly 114
Mouse Xcl1-7707M Recombinant Mouse Xcl1 protein, His & T7-tagged E.coli His/T7 Val26~Thr111 (Accession # P47993)
Mouse Xcl1-182M Recombinant Mouse Xcl1 protein E.coli N/A 93
Mouse XCL1-480MCL Recombinant Mouse XCL1 cell lysate Insect Cell N/A
Rat XCL1-6608R Recombinant Rat XCL1 Protein Mammalian Cell His
Rat Xcl1-7708R Recombinant Rat Xcl1 protein, His & GST-tagged E.coli His/GST Gly23~Thr113
Rat XCL1-6264R Recombinant Rat XCL1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat XCL1-6264R-B Recombinant Rat XCL1 Protein Pre-coupled Magnetic Beads HEK293
Rat Xcl1-638R Recombinant Rat Xcl1 protein E.coli N/A 93
Canine XCL1-169C Recombinant Canine XCL1, His tagged Insect Cell His
Canine XCL1-001CCL Recombinant Canine XCL1 cell lysate Insect Cell N/A
Cynomolgus Monkey XCL1-1187C Recombinant Cynomolgus XCL1 Protein, His-tagged Insect Cell His
Cynomolgus Monkey XCL1-452CCL Recombinant Cynomolgus XCL1 cell lysate Insect Cell N/A
Rhesus Macaque XCL1-5228R Recombinant Rhesus monkey XCL1 Protein, His-tagged Mammalian Cell His
Rhesus Macaque XCL1-5041R Recombinant Rhesus Macaque XCL1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque XCL1-5041R-B Recombinant Rhesus Macaque XCL1 Protein Pre-coupled Magnetic Beads HEK293
Chicken XCL1-6603C Recombinant Chicken XCL1 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • XCL1 Related Articles
  • XCL1 Related Gene Family
  • XCL1 Related Research Area

XCL1 involved in several pathways and played different roles in them. We selected most pathways XCL1 participated on our site, such as Cytokine-cytokine receptor interaction, Chemokine signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with XCL1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Cytokine-cytokine receptor interactionTNFRSF11B;Il6ra;CRFB2;CRFB16;CXCR4;TGFBR1B;CSF3;CCR3;IL28A
Chemokine signaling pathwayGM13306;CXCL6;CDC42;VAV1;CCL21;NFKB1;CXCR2;CCR6;CCL20

XCL1 has several biochemical functions, for example, CCR chemokine receptor binding, chemokine activity, chemokine receptor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by XCL1 itself. We selected most functions XCL1 had, and list some proteins which have the same functions with XCL1. You can find most of the proteins on our site.

Function Related Protein
CCR chemokine receptor bindingCCL33.3;CCL21;XCL2;CCL3L1;CCL20A.3;CCL17;CCL15;CCL8;CCL25B
chemokine activityCCL13;Ccl21c;PF4V1;Ccl9;CCL19A.1;CXCL13;CCL26;CCL15;CCL39.1
chemokine receptor bindingCCL25;Ccl21a;CXCL12;CCL19;Ccl21c;XCL1;CCL21B;CCL5;CCRL2
protein homodimerization activityGCH1;MAOB;CBX5;DAPK3;MSH2;GRPEL1;PLD6;MFF;GABRR1

XCL1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with XCL1 here. Most of them are supplied by our site. Hope this information will be useful for your research of XCL1.

Fossum, E; Grodeland, G; et al. Vaccine molecules targeting Xcr1 on cross-presenting DCs induce protective CD8(+) T-cell responses against influenza virus. EUROPEAN JOURNAL OF IMMUNOLOGY 45:624-635(2015).
Hartung, E; Becker, M; et al. Induction of Potent CD8 T Cell Cytotoxicity by Specific Targeting of Antigen to Cross-Presenting Dendritic Cells In Vivo via Murine or Human XCR1. JOURNAL OF IMMUNOLOGY 194:1069-1079(2015).
  • Q&As
  • Reviews

Q&As (5)

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What is known about the regulation of XCL1 expression, and how do various stimuli modulate its secretion in the context of inflammatory responses and immune activation? 01/22/2022

XCL1 expression is regulated by various stimuli, including inflammatory signals. Understanding how these stimuli modulate XCL1 secretion provides insights into its dynamic role in immune activation.

How does XCL1 influence the differentiation and function of dendritic cells, and are there implications for the modulation of adaptive immune responses? 03/01/2021

XCL1 influences the differentiation and function of dendritic cells, affecting the priming and activation of T cells. Understanding these processes has implications for modulating adaptive immune responses in various contexts.

How does XCL1 contribute to the formation of immune synapses between dendritic cells and T cells, and what molecular events underlie this process? 07/14/2020

XCL1 is involved in the formation of immune synapses between dendritic cells and T cells. Molecular events include the coordinated expression of adhesion molecules and the release of other signaling molecules.

Can you discuss the molecular mechanisms through which XCL1 interacts with its receptor XCR1, and how this interaction influences immune cell function? 02/26/2019

XCL1 binds to its receptor XCR1, initiating intracellular signaling cascades. This interaction influences immune cell function by directing the migration and activation of specific immune cell subsets.

In infectious diseases, particularly viral infections, what evidence supports the involvement of XCL1 in the host immune response, and how might it influence the outcome of infections? 09/20/2018

XCL1 is implicated in the host immune response to viral infections. Its role in recruiting and activating immune cells may influence the outcome of infections, impacting viral clearance and immune memory.

Customer Reviews (3)

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Reviews
03/30/2022

    Consistent high quality, responsive customer service, and seamless delivery

    07/10/2019

      Commendable product quality, professional customer service, and punctual delivery.

      09/05/2018

        Outstanding product quality, swift delivery, and helpful customer service. Highly recommend!

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