XCL1
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Official Full Name
chemokine (C motif) ligand 1
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Overview
Lymphotactin (LTN); is a chemokine produced mainly by activated CD8+ T-cells and directs migration of CD4+ and CD8+ lymphocytes and natural killer (NK); cells.1 LTN plays an important role in maintaining the integrity of the epithelium and in mucosal immu -
Synonyms
XCL1; chemokine (C motif) ligand 1; lymphotactin; lymphotaxin; cytokine SCM-1; c motif chemokine 1; small-inducible cytokine C1; small inducible cytokine subfamily C, member 1 (lymphotactin); LTN; ATAC; Lptn; SCM-1; Scyc1; SCM-1a; AI661682;
- Recombinant Proteins
- Cell & Tissue Lysates
- Protein Pre-coupled Magnetic Beads
- Canine
- Chicken
- Cynomolgus Monkey
- Human
- Mouse
- Rat
- Rhesus Macaque
- CHO
- E.coli
- HEK293
- Insect Cell
- Mammalian Cell
- Biotin
- Fc
- Fc, mutant
- His
- His (Fc)
- Avi
- His|Fc
- His|GST
- His|S
- His|T7
- N/A
- N
- GST
- Involved Pathway
- Protein Function
- Interacting Protein
- XCL1 Related Articles
- XCL1 Related Gene Family
- XCL1 Related Research Area
XCL1 involved in several pathways and played different roles in them. We selected most pathways XCL1 participated on our site, such as Cytokine-cytokine receptor interaction, Chemokine signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with XCL1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name | Pathway Related Protein |
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Cytokine-cytokine receptor interaction | TNFRSF11B;Il6ra;CRFB2;CRFB16;CXCR4;TGFBR1B;CSF3;CCR3;IL28A |
Chemokine signaling pathway | GM13306;CXCL6;CDC42;VAV1;CCL21;NFKB1;CXCR2;CCR6;CCL20 |
XCL1 has several biochemical functions, for example, CCR chemokine receptor binding, chemokine activity, chemokine receptor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by XCL1 itself. We selected most functions XCL1 had, and list some proteins which have the same functions with XCL1. You can find most of the proteins on our site.
Function | Related Protein |
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CCR chemokine receptor binding | CCL33.3;CCL21;XCL2;CCL3L1;CCL20A.3;CCL17;CCL15;CCL8;CCL25B |
chemokine activity | CCL13;Ccl21c;PF4V1;Ccl9;CCL19A.1;CXCL13;CCL26;CCL15;CCL39.1 |
chemokine receptor binding | CCL25;Ccl21a;CXCL12;CCL19;Ccl21c;XCL1;CCL21B;CCL5;CCRL2 |
protein homodimerization activity | GCH1;MAOB;CBX5;DAPK3;MSH2;GRPEL1;PLD6;MFF;GABRR1 |
XCL1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with XCL1 here. Most of them are supplied by our site. Hope this information will be useful for your research of XCL1.
- Q&As
- Reviews
Q&As (5)
Ask a questionXCL1 expression is regulated by various stimuli, including inflammatory signals. Understanding how these stimuli modulate XCL1 secretion provides insights into its dynamic role in immune activation.
XCL1 influences the differentiation and function of dendritic cells, affecting the priming and activation of T cells. Understanding these processes has implications for modulating adaptive immune responses in various contexts.
XCL1 is involved in the formation of immune synapses between dendritic cells and T cells. Molecular events include the coordinated expression of adhesion molecules and the release of other signaling molecules.
XCL1 binds to its receptor XCR1, initiating intracellular signaling cascades. This interaction influences immune cell function by directing the migration and activation of specific immune cell subsets.
XCL1 is implicated in the host immune response to viral infections. Its role in recruiting and activating immune cells may influence the outcome of infections, impacting viral clearance and immune memory.
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