Creative BioMart to Present at
                        BIO-Europe Spring Creative BioMart to Present at AACR Annual Meeting|Apr. 5-10, 2024|Booth #2953

Recombinant Rat Xcl1 protein

Cat.No. : Xcl1-638R
Product Overview : Recombinant Rat Xcl1 protein was expressed in E.coli.
  • Specification
  • Gene Information
  • Related Products
Description : The protein's mouse homolog is a cytokine with chemotactic activity for lymphocytes but not for monocytes or neutrophils.
Source : E.coli
Species : Rat
Form : Lyophilized from a 0.2 μm filtered concentrated solution in PBS, pH 7.4.
Bio-activity : Fully biologically active when compared to standard. The ED50 as determined by a chemotaxis bioassay using human XCR1 transfected murine BaF3 cells is less than 100 ng/ml, corresponding to a specific activity of > 1.0 × 10⁴ IU/mg.
Molecular Mass : Approximately 10.0 kDa, a single non-glycosylated polypeptide chain containing 93 amino acids.
Protein length : 93
AA Sequence : VGTEVLQESICVSLRTQRLPVQKIK TYTIKEGAMRAVIFVTKRGLRICAD PQAKWVKTAIKTVDGRASASKSKAE TIPTQAQRSASTAVTLTG
Endotoxin : Less than 0.1 EU/μg of rRtLymphotactin/XCL1 as determined by LAL method.
Purity : >97% by SDS-PAGE and HPLC analyses.
Storage : Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 centigrade as supplied. 1 month, 2 to 8 centigrade under sterile conditions after reconstitution. 3 months, -20 to -70 centigrade under sterile conditions after reconstitution.
Reconstitution : We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1 % BSA to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportioned into working aliquots and stored at ≤ -20 centigrade. Further dilutions should be made in appropriate buffered solutions.
Gene Name : Xcl1
Official Symbol : Xcl1
Synonyms : XCL1; chemokine (C motif) ligand 1; lymphotactin; cytokine SCM-1; c motif chemokine 1; small-inducible cytokine C1; small inducible cytokine subfamily C, member 1 (lymphotactin); Ltn; Scyc1;
Gene ID : 171371
mRNA Refseq : NM_134361
Protein Refseq : NP_599188
UniProt ID : P51672

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

Inquiry

  • Q&As
  • Reviews

Q&As (5)

Ask a question
What is known about the regulation of XCL1 expression, and how do various stimuli modulate its secretion in the context of inflammatory responses and immune activation? 01/22/2022

XCL1 expression is regulated by various stimuli, including inflammatory signals. Understanding how these stimuli modulate XCL1 secretion provides insights into its dynamic role in immune activation.

How does XCL1 influence the differentiation and function of dendritic cells, and are there implications for the modulation of adaptive immune responses? 03/01/2021

XCL1 influences the differentiation and function of dendritic cells, affecting the priming and activation of T cells. Understanding these processes has implications for modulating adaptive immune responses in various contexts.

How does XCL1 contribute to the formation of immune synapses between dendritic cells and T cells, and what molecular events underlie this process? 07/14/2020

XCL1 is involved in the formation of immune synapses between dendritic cells and T cells. Molecular events include the coordinated expression of adhesion molecules and the release of other signaling molecules.

Can you discuss the molecular mechanisms through which XCL1 interacts with its receptor XCR1, and how this interaction influences immune cell function? 02/26/2019

XCL1 binds to its receptor XCR1, initiating intracellular signaling cascades. This interaction influences immune cell function by directing the migration and activation of specific immune cell subsets.

In infectious diseases, particularly viral infections, what evidence supports the involvement of XCL1 in the host immune response, and how might it influence the outcome of infections? 09/20/2018

XCL1 is implicated in the host immune response to viral infections. Its role in recruiting and activating immune cells may influence the outcome of infections, impacting viral clearance and immune memory.

Customer Reviews (3)

Write a review
Reviews
03/30/2022

    Consistent high quality, responsive customer service, and seamless delivery

    07/10/2019

      Commendable product quality, professional customer service, and punctual delivery.

      09/05/2018

        Outstanding product quality, swift delivery, and helpful customer service. Highly recommend!

        Ask a Question for All Xcl1 Products

        Required fields are marked with *

        My Review for All Xcl1 Products

        Required fields are marked with *

        0

        Inquiry Basket

        cartIcon
        logo

        FOLLOW US

        Terms and Conditions        Privacy Policy

        Copyright © 2024 Creative BioMart. All Rights Reserved.

        Contact Us

        • /

        Stay Updated on the Latest Bioscience Trends