Active Recombinant Cynomolgus/Rhesus IL21R Protein, Fc-tagged

• Cat.No.: IL21R-1225C
• Product Overview: Recombinant cynomolgus IL21R (XP_005591578.1) (Met1-Pro236) was expressed with the Fc region of human IgG1 at the C-terminus. Cynomolgus and Rhesus IL21R sequences are identical.

Specification

• Source: HEK293
• Species: Cynomolgus/Rhesus
• Tag: Fc
• Predicted N Terminal: Cys 20
• Form: Lyophilized from sterile PBS, pH 7.4, 5%~8% trehalose and mannitol.
• Bio-activity: 1. Measured by its binding ability in a functional ELISA. 2. Immobilized human IL21 at 10 μg/mL (100 μL/well) can bind Cynomolgus IL21R-Fc. The EC50 of Cynomolgus IL21R-Fc is 0.11-0.25 μg/mL.
• Molecular Mass: The recombinant cynomolgus IL21R consists 458 amino acids and predicts a molecular mass of 52 kDa.
• Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.
• Purity: >90 % as determined by SDS-PAGE.
• Stability: Samples are stable for up to twelve months from date of receipt at -70ºC.
• Storage: Store it under sterile conditions at -20ºC~-70ºC. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
• Reconstitution: It is recommended that sterile water be added to the vial to prepare a stock solution of 0.25 ug/ul. Centrifuge the vial at 4℃ before opening to recover the entire contents.

Gene Information

• Gene Name: IL21R interleukin 21 receptor [ Macaca fascicularis ]
• Official Symbol: IL21R
• Synonyms: interleukin 21 receptor; Interleukin-21 receptor
• Gene ID: 102135042
• Chromosome Location: chromosome: 20
• Pathway: Cytokine-cytokine receptor interaction, organism-specific biosystem; Inflammatory bowel disease (IBD), organism-specific biosystem; TNF signaling pathway, conserved biosystem; Jak-STAT signaling pathway, organism-specific biosystem