Active Recombinant Human CCL4 Protein (69 aa)
| Cat.No. : | CCL4-219C |
| Product Overview : | Recombinant MIP-1 beta/CCL4 produced in CHO is a polypeptide chain containing 69 amino acids. A fully biologically active molecule, rhMIP-1 beta/CCL4 has a molecular mass of 10-19 kDa analyzed by reducing SDS-PAGE and is obtained by chromatographic techniques. |
- Specification
- Gene Information
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| Description : | Macrophage inflammatory protein 1 beta (MIP-1β), also known as Chemokine (C-C motif) ligand 4 (CCL4), is a small cytokine belonging to the CC chemokine family. It is a chemo attractant for natural killer cells, monocytes and a variety of other immune cells. MIP-1β is a major HIV-suppressive factor produced by CD8+ T cells. Perforin-low memory CD8+ T cells are the most common T-cells that normally synthesize MIP-1-beta in humans. MIP-1β has been shown to interact with CCL3. It can signal through the CCR5 receptor. |
| Source : | CHO |
| Species : | Human |
| Form : | Sterile Filtered White lyophilized (freeze-dried) powder. |
| Bio-activity : | The EC50 value of human MIP-1 beta/CCL4 on Ca^2+ mobilization assay in CHO-K1/Gα15/hCCR5 cells (human Gα15 and human CCR5 stably expressed in CHO-K1 cells) is less than 150 ng/mL. |
| Molecular Mass : | 10-19 kDa, observed by reducing SDS-PAGE. |
| Protein Length : | 69 |
| AA Sequence : | APMGSDPPTACCFSYTARKLPRNFV VDYYETSSLCSQPAVVFQTKRSKQV CADPSESWVQEYVYDLELN |
| Endotoxin : | < 0.2 EU/μg, determined by LAL method. |
| Purity : | > 95% as analyzed by SDS-PAGE and HPLC. |
| Storage : | Lyophilized recombinant Human MIP-1β/CCL4 remains stable up to 6 months at -80 centigrade from date of receipt. Upon reconstitution, Human MIP-1β/CCL4 should be stable up to 1 week at 4 centigrade or up to 3 months at -20 centigrade. |
| Storage Buffer : | Lyophilized after extensive dialysis against PBS. |
| Reconstitution : | Reconstituted in ddH2O or PBS at 100 μg/mL. |
| Gene Name : | CCL4 chemokine (C-C motif) ligand 4 [ Homo sapiens ] |
| Official Symbol : | CCL4 |
| Synonyms : | CCL4; chemokine (C-C motif) ligand 4; LAG1, SCYA4, small inducible cytokine A4 (homologous to mouse Mip 1b); C-C motif chemokine 4; Act 2; AT744.1; MIP 1 beta; PAT 744; SIS-gamma; MIP-1-beta(1-69); CC chemokine ligand 4; secreted protein G-26; T-cell activation protein 2; small-inducible cytokine A4; lymphocyte-activation gene 1; G-26 T-lymphocyte-secreted protein; lymphocyte activation gene 1 protein; macrophage inflammatory protein 1-beta; small inducible cytokine A4 (homologous to mouse Mip-1b); ACT2; G-26; HC21; LAG1; LAG-1; MIP1B; SCYA2; SCYA4; MIP1B1; MIP-1-beta; MGC104418; MGC126025; MGC126026; |
| Gene ID : | 6351 |
| mRNA Refseq : | NM_002984 |
| Protein Refseq : | NP_002975 |
| MIM : | 182284 |
| UniProt ID : | P13236 |
Products Types
| ◆ Recombinant Protein | ||
| Ccl4-77M | Active Recombinant Mouse Ccl4 Protein (Ala24-Asn92), N-His tagged, Animal-free, Carrier-free | +Inquiry |
| CCL4-2936H | Recombinant Human CCL4 Protein | +Inquiry |
| CCL4-934R | Recombinant Rat CCL4 Protein (Ala24-Asn92), His-tagged | +Inquiry |
| CCL4-2149H | Recombinant Human CCL4 Protein, His-tagged | +Inquiry |
| CCL4-2150H | Recombinant Human CCL4 Protein, His-tagged | +Inquiry |
| ◆ Lysates | ||
| CCL4-7721HCL | Recombinant Human CCL4 293 Cell Lysate | +Inquiry |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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