Ccl4 Protein

Ccl4

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Ccl4

Official Full Name chemokine (C-C motif) ligand 4
Background CCL4, also known as Macrophage inflammatory protein-1β (MIP-1β) is a CC chemokine with specificity for CCR5 receptors. It is a chemoattractant for natural killer cells, monocytes and a variety of other immune cells. CCL4 is a major HIV-suppressive factor produced by CD8+ T cells. Perforin-low memory CD8+ T cells that normally synthesize MIP-1-beta.
Synonyms Ccl4; chemokine (C-C motif) ligand 4; MIP-1b; MIP 1 beta; Secreted protein G 26; ACT 2; ACT-2; ACT2; AT744.1; CC chemokine ligand 4; CCL4; CCL4_HUMAN; ccl4l 1; CCL4L1; Chemokine CC Motif Ligand 4; G 26 T lymphocyte secreted protein; G-26 T-lymphocyte-secreted protein; HC21; LAG 1; LAG-1; LAG1; Lymphocyte activation gene 1; Lymphocyte activation gene 1 protein; Macrophage inflammatory protein 1 beta; Macrophage inflammatory protein 1-beta; MGC104418; MGC126025; MGC126026; MIP-1-beta; MIP-1-beta(1-69); MIP-1-beta(3-69); MIP1 beta; MIP1B; MIP1B1; PAT 744; Protein H400; SCYA2; SCYA4; Secreted protein G26; SIS gamma; SIS-gamma; Small inducible cytokine A4; Small-inducible cytokine A4; T cell activation protein 2; T-cell activation protein 2; MIP-1β; Macrophage inflammatory protein-1β
    • Species :
    • Atlantic Salmon
    • Canine
    • Cattle
    • Chicken
    • Cotton Rat
    • Cynomolgus Monkey
    • Dog
    • Human
    • Mouse
    • Pig
    • Rabbit
    • Rat
    • Source :
    • CHO
    • E. coli
    • E.coli
    • HEK293
    • HEK293F
    • HEK293T
    • Human Cell
    • Human Cells
    • Mammalian Cell
    • S.frugiperda
    • Wheat Germ
    • Yeast
    • Tag :
    • Biotin
    • DYKDDDDK
    • Fc
    • GST
    • His
    • Myc/DDK
    • N/A
    • N-His
    • Strep II
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human CCL4-119H Active Recombinant Human Chemokine (C-C Motif) Ligand 4, MIgG2a Fc-tagged CHO Fc Inquiry
    Human CCL4-16H Active Recombinant Human CCL4 yeast N/A Inquiry
    Human CCL4-183H Active Recombinant Human Chemokine (C-C Motif) Ligand 4, HIgG1 Fc-tagged, mutant CHO Fc Inquiry
    Human CCL4-185H Active Recombinant Human Chemokine (C-C Motif) Ligand 4, HIgG1 Fc-tagged CHO Fc Inquiry
    Canine CCL4-421C Active Recombinant Canine Chemokine (C-C motif) Ligand 4 E.coli N/A Inquiry
    Canine CCL4-631C Active Recombinant Canine CCL4 E.coli N/A Inquiry
    Cotton Rat Ccl4-386C Active Recombinant Cotton Rat Ccl4 E.coli N/A Inquiry
    Mouse Ccl4-01M Active GMP Recombinant Mouse Ccl4 Protein, His-Tagged E.coli His Inquiry
    Human CCL4-0640H Recombinant Human CCL4 Protein, GST-Tagged Wheat Germ GST Inquiry
    Human CCL4-10850H Recombinant Human CCL4, GST-tagged E.coli GST Inquiry
    Human CCL4-134H Recombinant Human CCL4, Fc-tagged CHO Fc Inquiry
    Human CCL4-159H Recombinant Human Chemokine (C-C motif) Ligand 4 S.frugiperda N/A Inquiry
    Human CCL4-247H Recombinant Human CCL4, His-tagged Yeast His Inquiry
    Human CCL4-290H Recombinant Human CCL4, StrepII-tagged Human Cell Strep II Inquiry
    Human CCL4-294H Recombinant Human CCL4 protein E.coli N/A Inquiry
    Human CCL4-710H Recombinant Human CCL4 protein, His & GST-tagged E.coli His/GST Inquiry
    Human CCL4-77H Recombinant Human CCL4 Yeast N/A Inquiry
    Mouse Ccl4-105M Recombinant Murine Chemokine (C-C Motif) Ligand 4 E.coli N/A Inquiry
    Mouse Ccl4-615M Recombinant Mouse Ccl4 protein E.coli N/A Inquiry
    Mouse Ccl4-711M Recombinant Mouse Ccl4 protein, His-tagged E.coli His Inquiry
    Mouse CCL4-75M Recombinant Mouse CCL4 Yeast N/A Inquiry
    Rat Ccl4-106R Recombinant Rat Chemokine (C-C Motif) Ligand 4 E.coli N/A Inquiry
    Rat CCL4-1214R Recombinant Rat CCL4 Protein Mammalian Cell His Inquiry
    Rat Ccl4-634R Recombinant Rat Ccl4 protein E.coli N/A Inquiry
    Rat Ccl4-712R Recombinant Rat Ccl4 protein, His-tagged E.coli His Inquiry
    Rat CCL4-74R Recombinant Rat CCL4 Yeast N/A Inquiry
    Dog CCL4-709D Recombinant Dog CCL4 protein, His & GST-tagged E.coli His/GST Inquiry
    Canine CCL4-76C Recombinant Canine CCL4 Yeast N/A Inquiry
    Chicken CCL4-137C Recombinant Chicken Chemokine (C-C motif) Ligand 4 Yeast N/A Inquiry
    Chicken CCL4-2235C Recombinant Chicken CCL4 Mammalian Cell His Inquiry
    Rabbit CCL4-713R Recombinant Rabbit CCL4 protein, His & GST-tagged E.coli His/GST Inquiry
    Pig CCL4-146S Recombinant Swine Chemokine (C-C motif) Ligand 4 Yeast N/A Inquiry
    Cattle CCL4-708C Recombinant Cattle CCL4 protein, His & GST-tagged E.coli His/GST Inquiry
    Human CCL4-7721HCL Recombinant Human CCL4 293 Cell Lysate HEK293 N/A Inquiry
    Human CCL4-074C Recombinant Human CCL4 Protein (69 aa) E.coli Inquiry
    Human CCL4-1110H Recombinant Human CCL4 Protein, His-tagged HEK293F N-His Inquiry
    Human CCL4-1111H Recombinant Human CCL4 Protein, His-tagged HEK293F N-His Inquiry
    Human CCL4-151H Recombinant Human CCL4 Protein, DYKDDDDK-tagged Human Cells DYKDDDDK Inquiry
    Human CCL4-2149H Recombinant Human CCL4 Protein, His-tagged E.coli N-His Inquiry
    Human CCL4-2150H Recombinant Human CCL4 Protein, His-tagged E.coli N-His Inquiry
    Human CCL4-219C Recombinant Human CCL4 Protein (69 aa) CHO Inquiry
    Human CCL4-25H Recombinant Human CCL4 Protein E.coli Inquiry
    Mouse Ccl4-26M Recombinant Mouse CCL4 Protein E.coli Inquiry
    Human CCL4-329C Recombinant Human CCL4 Protein (69 aa) E.coli Inquiry
    Human CCL4-71H Recombinant Human CCL4 Protein E.coli Inquiry
    Human CCL4-79H Recombinant Human CCL4 Protein, Biotin-tagged E.coli Biotin Inquiry
    Human CCL4-2936H Recombinant Human CCL4 Protein E.coli N/A Inquiry
    Human CCL4-6531H Recombinant Human CCL4 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK Inquiry
    Mouse Ccl4-2038M Recombinant Mouse Ccl4 Protein E. coli Inquiry
    Rat CCL4-934R Recombinant Rat CCL4 Protein (Ala24-Asn92), His-tagged Yeast His Inquiry
    Cynomolgus Monkey CCL4-4390C Recombinant Cynomolgus Monkey CCL4 Protein Yeast N/A Inquiry
    Atlantic Salmon CCL4-4396A Recombinant Atlantic Salmon CCL4 Protein Yeast N/A Inquiry

    Ccl4 involved in several pathways and played different roles in them. We selected most pathways Ccl4 participated on our site, such as Cytokine-cytokine receptor interaction, Chemokine signaling pathway, NF-kappa B signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with Ccl4 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Cytokine-cytokine receptor interaction GH1; BMPR1B; IL4; TNFRSF10A; CD40LG; IFNA14; IL6; CCL20; TNFRSF21; IL22RA2
    Chemokine signaling pathway GRB2; PLCB4; DOCK2; HRAS; PF4; RELA; CCL1; CCR1; STAT1; CCL11
    NF-kappa B signaling pathway TRAF3; TRAF6; TNFSF11; TAB2; CCL21; VCAM1; IRAK4; RELB; TNF; XIAP
    Toll-like receptor signaling pathway PIK3R3; RELA; CCL3L1; MAPK13; IFNA7; TBK1; RIPK1; MAP3K7; FADD; TLR3
    Cytosolic DNA-sensing pathway LOC100033925; CCL4L2; TMEM173; IFNA1; POLR2F; POLR3K; POLR3D; DDX58; RELA; POLR1C
    Salmonella infection KLC1A; CCL4L2; MAPK12; KLC1; CCL4L1; IL8L2; IL-8; RAC1; MAPK8; WASLB

    Ccl4 has several biochemical functions, for example, CCR1 chemokine receptor binding, CCR5 chemokine receptor binding, chemokine activity. Some of the functions are cooperated with other proteins, some of the functions could acted by Ccl4 itself. We selected most functions Ccl4 had, and list some proteins which have the same functions with Ccl4. You can find most of the proteins on our site.

    Function Related Protein
    CCR1 chemokine receptor binding CCL3; CCL7; CCL5; CREB3; CCL4; CCL23
    CCR5 chemokine receptor binding JAK1; CCL4; CCL5; CCL3; CNIH4; STAT3
    chemokine activity AMCF-II; CKLF; CCL34B.4; CCL34B.9; CCL5; CCL35.1; CCL19A.1; CCL38A.4; PF4; CXCL10
    cytokine activity BMP7B; HMGB1B; Il2; IL16; GM13285; CMTM4; BMP7; IFNB; ADIPOQ; IFNG1-1
    identical protein binding TOPBP1; SERPINA1; ANXA4; ZNF703; COL7A1; TLE1; INHBA; CLDN17; GRIK5; MDM2
    protein binding RTP3; ITGB7; RAD9B; ASS1; BDKRB2; HLA-DRB4; ZNF544; C22orf29; PHB; SERTAD1

    Ccl4 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with Ccl4 here. Most of them are supplied by our site. Hope this information will be useful for your research of Ccl4.

    SLC30A2; IDE; glgX; rnb

    Pauta, M; Ribera, J; et al. Overexpression of angiopoietin-2 in rats and patients with liver fibrosis. Therapeutic consequences of its inhibition. LIVER INTERNATIONAL 35:1383-1392(2015).
    He, JB; Wang, H; et al. Blockade of Vascular Endothelial Growth Factor Receptor 1 Prevents Inflammation and Vascular Leakage in Diabetic Retinopathy. JOURNAL OF OPHTHALMOLOGY :-(2015).

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