Active Recombinant Human CD79B protein, Fc-tagged

Cat.No. : CD79B-2995H
Product Overview : Recombinant Human CD79B protein(Ala 29-Asp 159), fused with Fc tag, was expressed in HEK293.
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Source : HEK293
Species : Human
Tag : Fc
Form : Lyophilized from 0.22 μm filtered solution in Tris with Glycine, Arginine and NaCl, pH7.5. Normally trehalose is added as protectant before lyophilization.
Bio-activity : Immobilized Human CD79B, Fc Tag at 1 μg/mL (100 μL/well) can bind Anti-CD79B (Polatuzumab) Humanized Antibody with a linear range of 0.1-1 ng/mL.
Molecular Mass : This protein carries a human IgG1 Fc tag at the C-terminus.The protein has a calculated MW of 41.8 kDa. The protein migrates as 55-65 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Protein Length : Ala 29-Asp 159
Endotoxin : Less than 0.1 EU per μg by the LAL method.
Purity : >90% as determined by SDS-PAGE.
Storage : For long term storage, the product should be stored at lyophilized state at-20°C or lower.Please avoid repeated freeze-thaw cycles. This product is stable after storage at:-20°C to-70°C for 12 months in lyophilized state;-70°C for 3 months under sterile conditions after reconstitution.
Reconstitution : It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4°C before opening to recover the entire contents.
Gene Name : CD79B CD79b molecule, immunoglobulin-associated beta [ Homo sapiens ]
Official Symbol : CD79B
Synonyms : CD79B; CD79b molecule, immunoglobulin-associated beta; CD79B antigen (immunoglobulin associated beta) , IGB; B-cell antigen receptor complex-associated protein beta chain; B29; Ig-beta; B-cell-specific glycoprotein B29; immunoglobulin-associated B29 protein; CD79b antigen (immunoglobulin-associated beta); IGB; AGM6;
Gene ID : 974
mRNA Refseq : NM_000626
Protein Refseq : NP_000617
MIM : 147245
UniProt ID : P40259

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Customer Reviews (3)

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Reviews
04/26/2023

    Renowned for its reliability and consistency, this protein offers researchers the confidence to achieve accurate and reproducible results in their studies.

    11/16/2021

      The CD79B protein comes highly recommended for its outstanding performance in ELISA assays.

      10/26/2018

        One notable advantage of the CD79B protein is the excellent technical support provided by its manufacturer.

        Q&As (5)

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        How does CD79B-targeted immunotherapy differ from traditional chemotherapy in treating B cell malignancies? 03/27/2021

        CD79B-targeted immunotherapy aims to specifically target B cells, potentially reducing side effects compared to non-specific chemotherapy.

        How does CD79B contribute to the development of personalized treatment strategies for B cell diseases? 01/12/2021

        Analyzing CD79B expression helps tailor treatment plans, allowing for more personalized and effective approaches.

        Can CD79B be used as a biomarker for minimal residual disease in B cell malignancies? 05/13/2018

        Yes, monitoring CD79B levels can aid in detecting minimal residual disease, providing insights into treatment response.

        Are there any challenges or limitations associated with relying on CD79B as a diagnostic marker? 03/02/2017

        Variability in CD79B expression among different B cell disorders may pose challenges in its use as a standalone diagnostic marker.

        Are there any clinical trials investigating the therapeutic potential of CD79B-targeted drugs? 01/22/2016

        Yes, several clinical trials are exploring the efficacy of CD79B-targeted drugs in various B cell disorders.

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