Active Recombinant Human EGFL7 protein(Tyr24-Ser273), His-tagged

Cat.No. : EGFL7-3077H
Product Overview : Recombinant Human EGFL7 (NP_057299.1) (Tyr 24-Ser 273) was expressed in Insect Cells, fused with a polyhistidine tag at the N-terminus.
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Source : Insect Cells
Species : Human
Tag : N-His
Protein length : Tyr24-Ser273
Form : Lyophilized from sterile 100mM Glycine, 10mM NaCl, 10% glycerol, pH 7.0. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Bio-activity : 1. Measured by the ability of the immobilized protein to support the adhesion of NIH-3T3 mouse embryonic fibroblast cells. When 5 × 10E4 cells/well areadded to EGFL7-His coated plates (1.25μg/mL and 100μL/well),approximately >45% will adhere specifically after 30 minutes at 37°C.
Molecular Mass : The recombinant human EGFL7 consists of 268 amino acids and predicts a molecular mass of 29.4 kDa. It migRates as an approximately 31 kDa band in SDS-PAGE under reducing conditions.
Endotoxin : < 1.0 EU per μg of the protein as determined by the LAL method
Purity : > 85 % as determined by SDS-PAGE
Storage : Samples are stable for up to twelve months from date of receipt at -20°C to -80°C. Store it under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution : It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4°C before opening to recover the entire contents.
Gene Name : EGFL7 EGF-like-domain, multiple 7 [ Homo sapiens ]
Official Symbol : EGFL7
Synonyms : EGFL7; EGF-like-domain, multiple 7; epidermal growth factor-like protein 7; ZNEU1; EGF-like protein 7; NOTCH4-like protein; vascular endothelial statin; multiple EGF-like domains protein 7; multiple epidermal growth factor-like domains protein 7; NEU1; VE-STATIN; RP11-251M1.2; MGC111117;
Gene ID : 51162
mRNA Refseq : NM_016215
Protein Refseq : NP_057299
MIM : 608582
UniProt ID : Q9UHF1

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (5)

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In what ways can EGFL7 be targeted for therapeutic interventions? 07/11/2021

Therapeutic interventions may involve targeting EGFL7 to modulate angiogenesis. This could be achieved through the development of drugs or therapies that either inhibit or enhance EGFL7 activity, depending on the clinical context.

How does EGFL7 interact with other proteins in the angiogenic pathway? 07/09/2020

EGFL7 interacts with various proteins involved in the angiogenic pathway, including growth factors and receptors. Understanding these interactions is essential for deciphering its role in angiogenesis.

Can EGFL7 be used as a prognostic marker in cancer patients? 07/07/2019

Some research suggests that EGFL7 expression levels may have prognostic value in predicting outcomes for cancer patients. Higher or lower expression levels could be indicative of disease severity or response to treatment.

How is EGFL7 expression regulated in normal and pathological conditions? 01/13/2017

The regulation of EGFL7 expression is complex and varies in different conditions. Understanding the regulatory mechanisms is crucial for developing targeted therapies that modulate EGFL7 expression appropriately.

Is EGFL7 targeted in any existing therapies? 08/13/2016

As of now, there are no widely accepted therapies specifically targeting EGFL7. However, ongoing research may lead to the development of targeted therapies in the future.

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08/18/2022

    These resources can enhance the efficiency and accuracy of experimental workflows and contribute to successful outcomes.

    11/01/2020

      Their collaboration, expertise, and customized solutions contribute to the successful execution of experiments, reliable data generation, and the advancement of scientific knowledge in the field.

      07/28/2017

        The manufacturer's support is crucial for researchers using EGFL7 protein in trials.

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