IL10RB-201H
Optional Service: Optional requirements on this protein
Product Overview :
The extracellular domain of human IL-10 (NP_000563.1)(Ser19-Lys178) (Glu151Lys) is fused to the N-terminus of the Fc region of mouse IgG2a was expressed in CHO cell.
Description :
The protein encoded by this gene belongs to the cytokine receptor family. It is an accessory chain essential for the active interleukin 10 receptor complex. Coexpression of this and IL10RA proteins has been shown to be required for IL10-induced signal transduction. This gene and three other interferon receptor genes, IFAR2, IFNAR1, and IFNGR2, form a class II cytokine receptor gene cluster located in a small region on chromosome 21
Source :
CHO cell
Species :
Human
Tag :
MIgG2a Fc-tagged
Form :
Lyophilized from 0.2μm-filtered solution in PBS.
Bio-activity :
Bioactivity demonstrated in cytokine synthesis inhibition assay, measuring inhibition of IL-6 production by PU5-1 cells.
Molecular Mass :
45 KDa (monomer)
AA Sequence :
Glu151Lys
Endotoxin :
<0.06 eu/μg as determined by lal test.>0.06>
Purity :
>98%, by SDS-PAGE under reducing conditions.
Stability :
Stable for at least 1 year after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C.
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.