Active Recombinant Human IL8 (28-99aa)
Cat.No. : | IL8-360H |
Product Overview : | Human IL8 (P10145, 28 a.a. - 99 a.a.) partial recombinant protein expressed in Escherichia coli. |
- Specification
- Gene Information
- Related Products
Cat. No. : | IL8-360H |
Description : | Interleukin-8 (IL8) is a chemokine produced by macrophages and other cell types such as epithelial cells. It is also synthesized by endothelial cells, which store IL8 in their storage vesicles, the Weibel-Palade bodies. In humans, the interleukin-8 protein is encoded by the IL8 gene. |
Sequence : | SAK ELRCQCIKTY SKPFHPKFIK ELRVIESGPH CANTEIIVKL SDGRELCLDP KENWVQRVVE KFLKRAENS |
Theoretical MW (kDa) : | 8 |
Form : | Lyophilized |
Preparation Method : | E. coli expression system |
Purity : | > 95% by SDS-PAGE and HPLC |
Endotoxin Level : | < 0.1 ng/ug (1 EU/ug) |
Activity : | Determined by its ability to chemoattract human peripheral blood neutrophils using a concentration range of 10.0-100.0 ng/mL. |
Application : | SDS-PAGE |
Storage Buffer : | Lyophilized from PBS, pH 7.5 |
Storage : | Store at -20°C on dry atmosphere. After reconstitution with deionized water, store at -20°C. Aliquot to avoid repeated freezing and thawing. |
Unitprot ID : | P10145 |
Gene Name : | IL8 interleukin 8 [ Homo sapiens ] |
Official Symbol : | IL8 |
Synonyms : | IL8; 3-10C; AMCF-I; CXCL8; Emoctakin; GCP-1; GCP1; IL-8; K60; LECT; LUCT; LYNAP; MDNCF; MONAP; NAF; NAP-1; NAP1; SCYB8; TSG-1; b-ENAP; emoctakin; C-X-C motif chemokine 8; Granulocyte chemotactic protein 1; Monocyte-derived neutrophil chemotactic factor; Monocyte-derived neutrophil-activating peptide; Neutrophil-activating protein 1; Protein 3-10C; T cell chemotactic factor; T-cell chemotactic factor; beta-thromboglobulin-like protein; chemokine (C-X-C motif) ligand 8; interleukin 8; lymphocyte-derived neutrophil-activating factor; neutrophil-activating peptide 1; small inducible cytokine subfamily B, member 8; Interleukin-8 |
Gene ID : | 3576 |
mRNA Refseq : | NM_000584 |
Protein Refseq : | NP_000575 |
MIM : | 146930 |
Chromosome Location : | 4q13-q21 |
Pathway : | Cytokine-cytokine receptor interaction; Epithelial cell signaling in Helicobacter pylori infection; Leukocyte transendothelial migration; Toll-like receptor signaling pathway; Signaling by GPCR |
Function : | chemokine activity; interleukin-8 receptor binding; protein binding |
Products Types
◆ Recombinant Protein | ||
IL8-4444H | Recombinant Human IL8 Protein, His (Fc)-Avi-tagged | +Inquiry |
IL8-5434M | Recombinant Macaca mulatta Interleukin 8 | +Inquiry |
IL8-190P | Recombinant Porcine IL8 Protein | +Inquiry |
IL8-189H | Recombinant Human IL8 Protein | +Inquiry |
IL8-191P | Recombinant Porcine IL8 Protein | +Inquiry |
◆ Lysates | ||
IL8-3002HCL | Recombinant Human IL8 cell lysate | +Inquiry |
IL8-3004HCL | Recombinant Human IL8 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (6)
Ask a questionActs as a chemical messenger in the immune system that regulates inflammation and attracts immune cells such as white blood cells.
Regulating tumor microenvironment, promoting tumor growth and metastasis, and can be used in tumor therapy research.
IL8 plays a role in regulating and promoting the migration and activation of inflammatory cells in the inflammatory response.
Can be used to treat inflammatory diseases (such as rheumatoid arthritis, psoriasis), tumors (such as lung cancer, breast cancer) and other diseases.
Yes, IL8 is closely related to immunotherapy, which can enhance the role of the immune system and assist in the treatment of certain diseases.
IL8 is generally prepared by gene recombination technology, and the IL8 gene is introduced into the appropriate expression system, and then expressed and purified.
Customer Reviews (3)
Write a reviewIL8 has good fluorescence and absorption properties.
NIPBL has good stability in different environments and is not easy to degrade.
Through animal models or in vitro experiments to evaluate the mechanism of the recombinant protein in related diseases, we found that the effect is very good.
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