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Active Recombinant Human/Mouse/Rat BMP2 Protein

Cat.No. : BMP2-06H
Product Overview : Recombinant Human/Mouse/Rat BMP2 Protein without tag was expressed in E. coli.
  • Specification
  • Gene Information
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Description : Bone morphogenetic protein 2 (BMP-2 or BMP2) is a member of the bone morphogenetic protein (BMP) family and functions as a potent inducer of bone and cartilage development. BMP proteins are synthesized as large precursor molecules which are cleaved by proteolytic enzymes. Bioactive BMP-2 consists of forming a homodimer or a heterodimer with a related BMP, such as BMP-7. BMP-2 signals through type I and type II receptor tyrosine kinases in conjuction with SMAD proteins to directly promote osteoblast differentiation. BMP-2 is also important during cardiac development and supports epicardial cell migration.
Source : E. coli
Species : Human/Mouse/Rat
Bio-activity : Alkaline phosphatase activity induced in ATDC-5 cells, ≤250 ng/mL
Molecular Mass : Dimer, 13.0/26.1 kDa (115/230 aa)
AA Sequence : MQAKHKQRKRLKSSCKRHPLYVDFS DVGWNDWIVAPPGYHAFYCHGECPF PLADHLNSTNHAIVQTLVNSVNSKI PKACCVPTELSAISMLYLDENEKVV LKNYQDMVVEGCGCR
Endotoxin : ≤1 EUs/μg, Kinetic LAL
Purity : ≥95%, Reducing and Non-Reducing SDS PAGE
Stability : 12 months from date of receipt when stored at -20 to -80 centigrade as supplied.
1 month when stored at 4 centigrade after reconstituting as directed.
3 months when stored at -20 to -80 centigrade after reconstituting as directed.
Storage : Storage Prior to Reconstitution: -20 centigrade
Storage Buffer : Lyophilized from a sterile (0.2 micron) filtered aqueous solution containing 0.1% Trifluoroacetic Acid (TFA)
Reconstitution : Sterile water at 0.1 mg/mL
Shipping : Room temperature
Instructions : Centrifuge vial before opening. Suspend the product by gently pipetting the above recommended solution down the sides of the vial. DO NOT VORTEX. Allow several minutes for complete reconstitution. For prolonged storage, dilute to working aliquots in a 0.1% BSA solution, store at -80 centigrade and avoid repeat freeze thaws.
Gene Name : BMP2 bone morphogenetic protein 2 [ Homo sapiens (human) ]
Official Symbol : BMP2
Synonyms : BMP2; bone morphogenetic protein 2; BMP2A; BMP-2A; bone morphogenetic protein 2A; BDA2;
Gene ID : 650
mRNA Refseq : NM_001200
Protein Refseq : NP_001191
MIM : 112261
UniProt ID : P12643

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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