Recombinant Human BMP2 protein, His-tagged BMP2-259H

Recombinant Human BMP2 protein, His-tagged

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Cat.No. :	BMP2-259H
Product Overview :	Recombinant Human BMP2 fused with His tag at N-terminal was expressed in E. coli.
Description :	This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer, which plays a role in bone and cartilage development. Duplication of a regulatory region downstream of this gene causes a form of brachydactyly characterized by a malformed index finger and second toe in human patients.
Source :	E. coli
Species :	Human
Tag :	His
Form :	50mM Tris, 8M Urea, pH8.0.
Molecular Mass :	42.4 kDa
Purity :	> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration :	>50 ug/mL as determined by microplate BCA method

Gene Name :	BMP2 bone morphogenetic protein 2 [ Homo sapiens ]
Official Symbol :	BMP2
Synonyms :	BMP2; bone morphogenetic protein 2; BMP2A; BMP-2A; bone morphogenetic protein 2A; BDA2;
Gene ID :	650
mRNA Refseq :	NM_001200
Protein Refseq :	NP_001191
MIM :	112261
UniProt ID :	P12643