Active Recombinant Mouse Gdnf Protein
Cat.No. : | Gdnf-278G |
Product Overview : | Recombinant Mouse Gdnf Protein without tag was expressed in CHO. |
- Specification
- Gene Information
- Related Products
Description : | Glial-Derived Neurotrophic Factor, also known as GDNF and ATF-1, is a neurotrophic factor belonging to the TGF-beta family. It is expressed in both central nervous system (CNS) and non-CNS tissues. GDNF signals through a receptor system composed of a RET and one of the four GFR alpha receptors. It promotes the survival and differentiation of dopaminergic neurons, and increases their high-affinity dopamine uptake. In a mouse Parkinson’s Disease model, GDNF has been shown to improve bradykinesia, rigidity, and postural instability. GDNF has also been shown to regulate kidney development, spermatogenesis and affect alcohol consumption. |
Source : | CHO |
Species : | Mouse |
Form : | Sterile Filtered White lyophilized (freeze-dried) powder. |
Bio-activity : | ED50 < 8μg/mL, measured in a bioassay using C6 cells. |
Molecular Mass : | 17-22 kDa, observed by reducing SDS-PAGE. |
AA Sequence : | MSPDKQAAALPRRERNRQAAAASPE NSRGKGRRGQRGKNRGCVLTAIHLN VTDLGLGYETKEELIFRYCSGSCES AETMYDKILKNLSRSRRLTSDKVGQ ACCRPVAFDDDLSFLDDNLVYHILR KHSAKRCGCI |
Endotoxin : | < 0.2 EU/μg, determined by LAL method. |
Purity : | > 95% as analyzed by SDS-PAGE and HPLC. |
Storage : | Lyophilized recombinant murine GDNF remains stable up to 6 months at -80 centigrade from date of receipt. Upon reconstitution, Murine GDNF should be stable up to 1 week at 4 centigrade or up to 2 months at -20 centigrade. |
Storage Buffer : | Lyophilized after extensive dialysis against PBS. |
Reconstitution : | Reconstituted in ddH2O or PBS at 100 μg/mL. |
Gene Name : | Gdnf glial cell line derived neurotrophic factor [ Mus musculus ] |
Official Symbol : | Gdnf |
Synonyms : | GDNF; glial cell line derived neurotrophic factor; glial cell line-derived neurotrophic factor; ATF; mGDNF; neurotrophic factor; astrocyte-derived trophic factor; AI385739; |
Gene ID : | 14573 |
mRNA Refseq : | NM_010275 |
Protein Refseq : | NP_034405 |
UniProt ID : | P48540 |
Products Types
◆ Recombinant Protein | ||
GDNF-108H | Recombinant Active Human GDNF Protein, His-tagged(C-ter) | +Inquiry |
GDNF-109M | Recombinant Mouse GDNF Protein | +Inquiry |
GDNF-01H | Recombinant Human GDNF Protein, His-tagged | +Inquiry |
GDNF-279G | Active Recombinant Human GDNF Protein | +Inquiry |
GDNF-7292H | Active Recombinant Human GDNF protein(Arg83-Ile185) | +Inquiry |
◆ Lysates | ||
GDNF-400RCL | Recombinant Rat GDNF cell lysate | +Inquiry |
GDNF-1549HCL | Recombinant Human GDNF cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
0
Inquiry Basket