Active Recombinant Mouse Il3 Protein (135 aa)
Cat.No. : | Il3-357I |
Product Overview : | Recombinant mouse Interleukin-3 (rmIL-3) produced in E. coli is a single non-glycosylated polypeptide chain containing of 135 amino acids. A fully biologically active molecule, rmIL-3 has a molecular mass of 15.2 kDa analyzed by non-reducing SDS-PAGE and is obtained by proprietary chromatographic techniques. |
- Specification
- Gene Information
- Related Products
Description : | Interleukin-3 (IL-3) is a pleiotropic cytokine belonging to the interleukin family. IL-3 shares similarities with Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF) and IL-5: they all have a four-helix bundle structure, are located on the same chromosomes in both human and mouse, are produced by activated T cells, and share receptors. The IL-3/IL-5/GM-CSF receptor family members are all heterodimeric, composed of a receptor-specific α chain and a common β chain. IL-3 is also called multi-colony stimulating factor since it stimulates the development and colony formation of multiple lineages of hematopoietic cells by activating intracellular pathways such as Ras-Raf-ERK and JAK/STAT. IL-3 inhibits apoptosis and promotes cell survival by targeting the anti-apoptotic bcl-2 gene family. |
Source : | E. coli |
Species : | Mouse |
Form : | Sterile Filtered White lyophilized (freeze-dried) powder. |
Bio-activity : | ED50 < 0.05 ng/mL, measured by a cell proliferation assay using M-NFS-60 cells, corresponding to a specific activity of > 2 × 10^7 units/mg. |
Molecular Mass : | 15.2 kDa, observed by non-reducing SDS-PAGE. |
Protein Length : | 135 |
AA Sequence : | MDTHRLTRTLNCSSIVKEIIGKLPE PELKTDDEGPSLRNKSFRRVNLSKF VESQGEVDPEDRYVIKSNLQKLNCC LPTSANDSALPGVFIRDLDDFRKKL RFYMVHLNDLETVLTSRPPQPASGS VSPNRGTVEC |
Endotoxin : | < 0.2 EU/μg, determined by LAL method. |
Purity : | > 95% by SDS-PAGE analysis. |
Storage : | Lyophilized recombinant mouse Interleukin-3 (rmIL-3) remains stable up to 6 months at -80 centigrade from date of receipt. Upon reconstitution, rmIL-3 remains stable up to 2 weeks at 4 centigrade or up to 3 months at -20 centigrade. |
Storage Buffer : | Lyophilized after extensive dialysis against PBS. |
Reconstitution : | Reconstituted in ddH2O at 100 μg/mL. |
Gene Name : | Il3 interleukin 3 [ Mus musculus ] |
Official Symbol : | Il3 |
Synonyms : | IL3; interleukin 3; interleukin-3; mast cell growth factor; P-cell-stimulating factor; hematopoietic growth factor; multipotential colony-stimulating factor; BPA; PSF; HCGF; Il-3; MCGF; Csfmu; |
Gene ID : | 16187 |
mRNA Refseq : | NM_010556 |
Protein Refseq : | NP_034686 |
UniProt ID : | P01586 |
Products Types
◆ Recombinant Protein | ||
Il3-027I | Active Recombinant Mouse Il3 Protein (135 aa) | +Inquiry |
IL3-5192H | Recombinant Human IL3 Protein, GST-tagged | +Inquiry |
IL3-167H | Active Recombinant Human IL3 Protein (Ala20-Phe152), C-His tagged, Animal-free, Carrier-free | +Inquiry |
IL3-1035D | Recombinant Dog IL3 Protein, His-tagged | +Inquiry |
IL3-168H | Active Recombinant Human IL3 Protein | +Inquiry |
◆ Lysates | ||
IL3-607HCL | Recombinant Human IL3 cell lysate | +Inquiry |
IL3-445RCL | Recombinant Rat IL3 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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