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Official Full Name interleukin 3
Background The protein encoded by this gene is a potent growth promoting cytokine. This cytokine is capable of supporting the proliferation of a broad range of hematopoietic cell types. It is involved in a variety of cell activities such as cell growth, differentiation and apoptosis. This cytokine has been shown to also possess neurotrophic activity, and it may be associated with neurologic disorders.
Synonyms Colony stimulating factor multiple; Hematopoietic growth factor; IL 3; IL-3; IL3; IL3_HUMAN; Interleukin 3 (colony stimulating factor, multiple); Interleukin 3; Interleukin-3; Mast cell growth factor; MCGF; MGC79398; MGC79399; Multi CSF; Multilineage colony stimulating factor; Multipotential colony stimulating factor; Multipotential colony-stimulating factor; OTTHUMP00000065963; P cell stimulating factor; P-cell-stimulating factor; BPA; PSF; HCGF; Csfmu; nterleukin-3; TTMUSP00000005831; ast cell growth factor
    • Species :
    • Bovine
    • Canine
    • Chicken
    • Dog
    • Human
    • Mouse
    • Rat
    • Rhesus
    • Rhesus Macaque
    • Source :
    • CHO
    • E.coli
    • HEK293
    • Hordeum Vulgare
    • Insect Cell
    • Mammalian Cell
    • Mouse
    • Nicotiana Benthamiana
    • S.cerevisiae
    • Wheat Germ
    • Yeast
    • Tag :
    • GST
    • His
    • T7
    • His-Avi
    • HQ
    • Met
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human IL3-077HG GMP Recombinant Human IL-3 protein, His-tagged HEK293 His
    Mouse Il3-107M Recombinant Mouse Il3 Protein E.coli
    Mouse Il3-108M Recombinant Mouse Il3 Protein E.coli
    Human IL3-131H Recombinant Human IL3 protein, His-Avi-tagged HEK293 His-Avi
    Mouse IL3-455M Recombinant Mouse IL3 Protein HEK293 N/A
    Mouse Il3-7242M Recombinant Mouse Il3 Protein, His-tagged Insect Cell His
    Human CSF3&IL3-5H Recombinant Human GM-CSF/IL-3 (PIXY321) Fusion Protein E.coli N/A
    Human IL3-08H Recombinant Human IL3 protein E.coli N/A
    Human IL3-106H Human Interleukin-3 (rDNA derived) Reference standard N/A
    Human IL3-120H Recombinant Human Interleukin 3 (Colony-stimulating Factor, Multiple) HEK293 N/A
    Human IL3-132H Recombinant Human Interleukin 3 (colony-stimulating factor, multiple), His-tagged Insect Cell His
    Human IL3-132HG GMP Recombinant Human IL3 protein E.coli N/A
    Human IL3-145H Recombinant Human IL3 Active, His-tagged Nicotiana Benthamiana His
    Human IL3-1556H Recombinant human IL3, Active, His-tagged Nicotiana Benthamiana His
    Human Il3-1922H Recombinant Human Il3 Protein Insect Cell N/A
    Human IL3-200H Recombinant Human IL3 CHO N/A
    Human IL3-275H Recombinant Human Interleukin 3 (Colony-Stimulating Factor, Multiple) S.cerevisiae N/A
    Human IL3-378H Recombinant Human IL3, His tagged Insect Cell His
    Human IL3-435H Recombinant Human IL3 Protein, His-tagged HEK293 His
    Human IL3-436H Recombinant Human IL3 Protein E.coli N/A
    Human IL3-503H Recombinant Human IL3 HEK293 N/A
    Human IL3-5192H Recombinant Human IL3 Protein, GST-tagged Wheat Germ GST
    Human IL3-56H Recombinant Human IL3, His-tagged E.coli His
    Human IL3-604H Recombinant Human Interleukin 3 (colony-stimulating factor, multiple), HQ-tagged Hordeum Vulgare HQ
    Human IL3-607HCL Recombinant Human IL3 cell lysate Insect Cell N/A
    Human IL3-639H Recombinant Human IL3 protein, His & GST-tagged E.coli His/GST
    Human IL3-8862H Recombinant Human IL3, His-tagged Hordeum Vulgare N/A
    Human IL3-88H Recombinant Human GMCSF/IL-3 Fusion Protein E.coli N/A
    Mouse Il3-09M Recombinant Mouse Il3 protein E.coli N/A
    Mouse Il3-114M Mouse Interleukin-3 (rDNA derived) Reference standard N/A
    Mouse Il3-366M Recombinant Mouse Il3 Protein, His-tagged Insect Cell His
    Mouse Il3-592M Recombinant Mouse Interleukin 3 Mouse N/A
    Mouse Il3-640M Recombinant Mouse Il3 protein, His & T7-tagged E.coli His/T7
    Mouse Il3-641M Recombinant Mouse Il3 protein, His & GST-tagged E.coli His/GST
    Mouse Il3-644M Recombinant Mouse Il3 E.coli Met
    Mouse ll3-542M Recombinant Mouse Iterleukin 3 Mouse N/A
    Rat IL3-1093R Recombinant Rat IL3 Protein, His-tagged Insect Cell His
    Rat IL3-445RCL Recombinant Rat IL3 cell lysate Insect Cell N/A
    Rat Il3-576R Recombinant Rat Il3 protein E.coli N/A
    Rat Il3-591R Recombinant Rat Interleukin 3 E.coli N/A
    Rat Il3-642R Recombinant Rat Il3 protein, His & T7-tagged E.coli His/T7
    Rat Il3-643R Recombinant Rat Il3 protein, His & GST-tagged E.coli His/GST
    Rhesus Macaque IL3-2250R Recombinant Rhesus monkey IL3 Protein, His-tagged Mammalian Cell His
    Rhesus IL3-539R Recombinant Rhesus IL3 protein E.coli N/A
    Dog IL3-362D Recombinant Dog Interleukin 3 (colony-stimulating factor, multiple) E.coli N/A
    Canine IL3-407D Recombinant Canine IL3 protein E.coli N/A
    Bovine IL3-4369B Recombinant Bovine IL3 Protein Yeast N/A
    Chicken IL3-1734C Recombinant Chicken IL3 Mammalian Cell His

    il3 involved in several pathways and played different roles in them. We selected most pathways il3 participated on our site, such as Cytokine-cytokine receptor interaction, PIK-Akt signaling pathway, Apoptosis, which may be useful for your reference. Also, other proteins which involved in the same pathway with il3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Cytokine-cytokine receptor interaction TNFRSF11A; IL2RGA; IL28RA; CCL3L1; NGFRB; GHRA; CSF3R; GM10591; OSMR; FASLG
    PIK-Akt signaling pathway LAMA4; ITGA5; THBS4; IKBKB; Itga10&Itgb1; FGF9; PPP2R5D; FGFR3; TNN; COL24A1
    Apoptosis ADD1; DYNLL2; AKT2; RIPK1L; TNFRSF10C; DAPK3; DERL3; IRAK4; IL1A; TRP53
    Jak-STAT signaling pathway GM13305; IL3RA; SOCS1; IFNA8; CTF1; PRP2; IFNB; PRLR; RAF1A; STAT3
    Hematopoietic cell lineage IL11; IL3; THPO; HLA-DRB5; ITGB3; CD19; MS4A1; IL5; IL9R; CD7
    Fc epsilon RI signaling pathway MAP2K6; PIK3R5; PDPK1; MAP2K3; RAC3; IL13; PIK3CD; LCP2; GAB2; MAP2K2
    Transcriptional misregulation in cancer EYA1; HOXA11; REL; MLL1; PRCC; DOT1L; LDB1; WNT16; FLT1; CD40

    il3 has several biochemical functions, for example, cytokine activity, growth factor activity, interleukin-3 receptor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by il3 itself. We selected most functions il3 had, and list some proteins which have the same functions with il3. You can find most of the proteins on our site.

    Function Related Protein
    cytokine activity HMGB1A; GDF6B; Flt3l; IL21; IFNG1-2; IL8L2; BMP3; VEGFA; FASLG; LFT1
    growth factor activity CLCF1; LFT1; BMP3; FGF12; GDF5; GDF11; NTF4; KLK1B4; FGF9; PSPN
    interleukin-3 receptor binding RNF41; IL3

    il3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with il3 here. Most of them are supplied by our site. Hope this information will be useful for your research of il3.


    Barr, TP; Kornberg, D; et al. Validation of endothelin B receptor antibodies reveals two distinct receptor-related bands on Western blot. ANALYTICAL BIOCHEMISTRY 468:28-33(2015).
    Abrishami, M; Pastushok, L; et al. Synthetic Anti-IL3 Receptor Antibodies As Therapeutics to Block Innate Imatinib Resistance in Chronic Myelogenous Leukemia. BLOOD 124:-(2014).

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