Active Recombinant Rat Csf1 Protein

Cat.No. : Csf1-221C
Product Overview : Recombinant Rat Csf1 Protein without tag was expressed in CHO.
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Description : Macrophage-Colony Stimulating Factor (M-CSF), also known as Colony Stimulating Factor-1 (CSF-1), can stimulate the survival, proliferation and differentiation of mononuclear phagocytes, in addition to the spreading and motility of macrophages. M-CSF is mainly produced by monocytes, macrophages, fibroblasts, and endothelial cells. M-CSF interaction with its receptor, c-fms, has been implicated in the growth, invasion, and metastasis of of several diseases, including breast and endometrial cancers.
Source : CHO
Species : Rat
Form : Sterile Filtered White lyophilized (freeze-dried) powder.
Bio-activity : ED50 < 2.5 ng/mL, measured in a cell proliferation assay using Murine M-NFS-60 cells, corresponding to a specific activity of > 4 × 10^5 units/mg.
Molecular Mass : 32-40 kDa, observed by non-reducing SDS-PAGE.
Endotoxin : < 0.2 EU/μg, determined by LAL method.
Purity : > 95% as analyzed by SDS-PAGE.
Storage : Lyophilized recombinant Rat Macrophage-Colony Stimulating Factor (M-CSF) remains stable up to 6 months at -80 centigrade from date of receipt. Upon reconstitution, rrM-CSF should be stable up to 1 week at 4 centigrade or up to 2 months at -20 centigrade.
Storage Buffer : Lyophilized after extensive dialysis against PBS.
Reconstitution : Reconstituted in ddH2O or PBS at 100 μg/mL.
Gene Name : Csf1 colony stimulating factor 1 (macrophage) [ Rattus norvegicus ]
Official Symbol : Csf1
Synonyms : CSF1; colony stimulating factor 1 (macrophage); macrophage colony-stimulating factor 1; MCSF; CSF-1;
Gene ID : 78965
mRNA Refseq : NM_023981
Protein Refseq : NP_076471
UniProt ID : Q8JZQ0

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.


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Customer Reviews (3)

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    The CSF1 protein is renowned for its exceptional quality and reliability, making it an ideal choice to fulfill my experimental requirements.


      With its high purity and stability, this protein ensures dependable and accurate results, which are crucial for the success of my research endeavors.


        Whether it is for investigating cellular pathways, studying protein functions, or exploring signaling cascades, the CSF1 protein offers unparalleled versatility and performance.

        Q&As (5)

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        How does CSF1 affect cancer progression? 09/20/2022

        CSF1 is implicated in tumor-associated macrophages, influencing tumor growth, invasion, and the tumor microenvironment.

        What are the potential side effects of CSF1 therapy? 07/11/2022

        Side effects may include immune-related adverse events, inflammation, and alterations in white blood cell counts.

        Can CSF1 therapy be combined with other treatments? 08/26/2020

        Yes, there is ongoing research on combining CSF1-targeted therapies with other immunotherapies or conventional treatments to enhance efficacy.

        What are the challenges in developing CSF1-based therapies? 09/26/2019

        Challenges include maintaining the balance of immune responses, potential off-target effects, and variability in patient responses.

        In what ways is CSF1 being researched for neurological disorders? 10/01/2018

        Studies are exploring its role in neuroinflammation, neuroprotection, and potential therapeutic interventions for conditions like Alzheimer's disease.

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