Active Recombinant Rat Fgf2 Protein (146 aa)
Cat.No. : | Fgf2-397F |
Product Overview : | Recombinant rat Fibroblast Growth Factor-basic (rrFGF-basic) produced in E. coli is a single non-glycosylated polypeptide chain containing 146 amino acids. A fully biologically active molecule, rrFGF-basic has a molecular mass of 16.4 kDa analyzed by reducing SDS-PAGE and is obtained by proprietary chromatographic techniques. |
- Specification
- Gene Information
- Related Products
Description : | Fibroblast Growth Factor-basic (FGF-basic), also known as FGF-2, is a pleiotropic cytokine and one of the prototypic members of the heparin-binding FGF family. Like other FGF family members, FGF-basic has the β trefoil structure. In vivo, FGF-basic is produced by a variety of cells, including cardiomycotes, fibroblasts, and vascular cells. FGF-basic regulates a variety of processes including cell proliferation, differentiation, survival, adhesion, motility, apoptosis, limb formation and wound healing. FGF-basic can be tumorigenic due to its role in angiogenesis and blood vessel remodeling. The angiogenic effects of FGF-basic can produce beneficial cardioprotection during acute heart injury. |
Source : | E. coli |
Species : | Rat |
Form : | Sterile Filtered White lyophilized (freeze-dried) powder. |
Bio-activity : | ED50 < 0.25 ng/mL, measured by a cell proliferation assay using 3T3 cells, corresponding to a specific activity of > 4 × 10^6 units/mg. |
Molecular Mass : | 16.4 kDa, observed by reducing SDS-PAGE. |
Protein Length : | 146 |
AA Sequence : | GPALPEDGGGAFPPGHFKDPKRLYC KNGGFFLRIHPDGRVDGVREKSDPH VKLQLQAEERGVVSIKGVCANRYLA MKEDGRLLASKCVTEECFFFERLES NNYNTYRSRKYSSWYVALKRTGQYK LGSKTGPGQKAILFLPMSAKS |
Endotoxin : | < 0.2 EU/μg, determined by LAL method. |
Purity : | > 95% by SDS-PAGE analysis. |
Storage : | Lyophilized recombinant rat Fibroblast Growth Factor-basic (rrFGF-basic) remains stable up to 6 months at -80 centigrade from date of receipt. Upon reconstitution, rrFGF-basic remains stable up to 2 weeks at 4 centigrade or up to 3 months at -20 centigrade. |
Storage Buffer : | Lyophilized after extensive dialysis against PBS. |
Reconstitution : | Reconstituted in ddH2O at 100 μg/mL. |
Gene Name : | Fgf2 fibroblast growth factor 2 [ Rattus norvegicus ] |
Official Symbol : | Fgf2 |
Synonyms : | FGF2; fibroblast growth factor 2; HBGF-2; basic fibroblast growth factor; heparin-binding growth factor 2; bFGF; Fgf-2; |
Gene ID : | 54250 |
mRNA Refseq : | NM_019305 |
Protein Refseq : | NP_062178 |
UniProt ID : | P13109 |
Products Types
◆ Recombinant Protein | ||
FGF2-401F | Active Recombinant Human FGF2 Protein (146 aa) | +Inquiry |
FGF2-4387R | Recombinant Rabbit FGF2 Protein | +Inquiry |
Fgf2-1489R | Recombinant Rat Fgf2 Protein, His-tagged | +Inquiry |
Fgf2-829M | Active Recombinant Mouse Fgf2 protein(Ala11-Ser154), His-tagged | +Inquiry |
Fgf2-061M | Active Recombinant Mouse Fgf2 Protein | +Inquiry |
◆ Native Protein | ||
FGF2-26551TH | Native Human FGF2 | +Inquiry |
◆ Lysates | ||
FGF2-638HCL | Recombinant Human FGF2 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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