CTLA4[Biotinylated]:B7-2 Inhibitor Screening Assay Kit

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CTLA4[Biotinylated]:B7-2 Inhibitor Screening Assay Kit

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Cat.No. : Kit-1713
Product Overview : B7-2 (CD86) signaling through CTLA4(CD152) has been shown to inhibit T cell activation. This co-inhibitory pathway can be overactive in many tumors, enabling cancers to escape the host"s immune system. CTLA4-blocking antibodies, including Ipilimumab (Yervoy) and Tremelimumab, have shown clinical efficacy in treating cancer.
Size : 96 reactions
Applications : This kit is useful for screening for inhibitors of CTLA4 binding to B7-2.
Storage : Stable at least 6 months from date of receipt, when stored as directed. Kit components require different storage conditions. Be sure to store each component at the proper temperature upon arrival

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