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CTLA4[Biotinylated]:B7-2 Inhibitor Screening Assay Kit
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Cat.No. : | Kit-1713 |
Product Overview : | B7-2 (CD86) signaling through CTLA4(CD152) has been shown to inhibit T cell activation. This co-inhibitory pathway can be overactive in many tumors, enabling cancers to escape the host"s immune system. CTLA4-blocking antibodies, including Ipilimumab (Yervoy) and Tremelimumab, have shown clinical efficacy in treating cancer. |
Size : | 96 reactions |
Applications : | This kit is useful for screening for inhibitors of CTLA4 binding to B7-2. |
Storage : | Stable at least 6 months from date of receipt, when stored as directed. Kit components require different storage conditions. Be sure to store each component at the proper temperature upon arrival |
◆ Recombinant Protein
CTLA4-1106H | Recombinant Human CTLA4 Protein (Met1-Phe162), HlgG1 Fc-tagged, Biotinylated | +Inquiry |
CTLA4-257H | Recombinant Human CTLA4 Protein, His-Avi-tagged, Biotinylated | +Inquiry |
CTLA4-499H | Recombinant Human CTLA4 Protein (Met1-Phe162), HIgG1 Fc-tagged | +Inquiry |
CTLA4-2073P | Recombinant CTLA4 Protein, His-Flag-StrepII-tagged | +Inquiry |
Ctla4-038M | Recombinant Mouse Ctla4 Protein, Fc-tagged | +Inquiry |
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◆ Lysates
CTLA4-1047CCL | Recombinant Cynomolgus CTLA4 cell lysate | +Inquiry |
CTLA4-2526HCL | Recombinant Human CTLA4 cell lysate | +Inquiry |
CTLA4-2179MCL | Recombinant Mouse CTLA4 cell lysate | +Inquiry |
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◆ Assay kits
Kit-1712 | CTLA4:B7-1[Biotinylated] Inhibitor Screening Assay Kit | +Inquiry |
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