Recombinant Human Adrenergic, Beta, Receptor Kinase 2, GST-tagged
| Cat.No. : |
ADRBK2-1179H |
| Product Overview : |
Recombinant humanADRBK2 is a serine/threonine kinase that is thought to act as a regulator ofreceptor function. |
- Specification
- Gene Information
- Related Products
| Cat. No. : |
ADRBK2-1179H |
| Description : |
ADRBK2(beta-ARK-2) also known as G-protein-coupled receptor kinase 3 (GRK3) is anenzyme that in humans is encoded by the ADRBK2 gene. The ADRBK2 specifically phosphorylates the agonist-occupiedform of the beta-adrenergic and related G protein-coupled receptors. |
| Source : |
Insect cells |
| Species : |
Human |
| Form : |
Liquid in 50 mMTris-HCl, pH 7.5 + 150 mM NaCl + 0.5 mM EDTA + 0.02%. Triton X-100 + 2 mM DTT+ 50% glycerol. |
| Molecular Weight : |
107.2 kDa |
| Concentration : |
0.44 mg/ml |
| Purity : |
> 90% asdetermined by SDS-PAGE analysis. |
| Storage : |
Stable for 6 monthsin working aliquots at -80°C. Avoid repeated freeze-thaw cycles. |
| OfficialSymbol : |
ADRBK2 |
| Gene Name : |
ADRBK2 adrenergic, beta, receptorkinase 2 [ Homo sapiens ] |
| Synonyms : |
ADRBK2; adrenergic,beta, receptor kinase 2; GRK3; BARK2; beta-adrenergic receptor kinase 2;beta-ARK-2; OTTHUMP00000196857; G-protein-coupled receptor kinase 3;Beta-ARK-2; EC 2.7.11; EC 2.7.11.15 |
| Gene ID : |
157 |
| mRNA Refseq : |
NM_005160 |
| Protein Refseq : |
NP_005151 |
| MIM : |
109636 |
| UniProt ID : |
P35626 |
| Chromosome Location : |
22q11; 22q12.1 |
| Pathway : |
Chemokine signalingpathway; Endocytosis; Glutamatergic synapse; IL-4 signaling Pathway;Olfactory transduction; Thromboxane A2 receptor signaling |
| Function : |
ATP binding;G-protein coupled receptor kinase activity; beta-adrenergic receptor kinaseactivity; nucleotide binding; protein kinase activity; signal transduceractivity; transferase activity, transferring phosphorus-containing groups |
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
