Native Human C-Reactive Protein, Pentraxin-Related

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Native Human C-Reactive Protein, Pentraxin-Related

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Cat. No. : CRP-5299H
Product Overview : Native human highpurified CRP was expressed in Human Pleural fluid.
Description : CRP is a proteinfound in the blood, the levels of which rise in response to inflammation. Itsphysiological role is to bind to phosphocholine expressed on the surface ofdead or dying cells (and some types of bacteria) in order to activate thecomplement system via the C1Q complex.
Source : HumanPleural fluid
Form : Liquid, Supplied as a solution in0.05 M Tris buffer containing 0.25 M Sodium Chloride, 0.005 M CalciumChloride, and 0.1% sodium azide, pH 8.0, filter sterilized through a 0.2 μMmembrane.
Concentration : 2.56 mg/ml
Purity : >98% by SDS Page
Storage : Centrifugevial prior to opening. Store at 4°C.
Pathways : Classical antibody-mediated complementactivation; Complement cascade; Creation of C4 and C2 activators; IL6-mediatedsignaling events; Initial triggering of complement; Innate Immune System;Selenium Pathway
Constructedfrom 1B09. :

Gene Name : CRPC-reactive protein, pentraxin-related [ Homo sapiens ]
Official Symbol : CRP
Synonyms : CRP; C-reactive protein,pentraxin-related; PTX1; pentraxin1; OTTHUMP00000033307; OTTHUMP00000033308;OTTHUMP00000033309; OTTHUMP00000033310; C-reactive protein; C-reactiveprotein (1-205); MGC149895; MGC88244
Gene ID : 1401
mRNA Refseq : NM_000567
Protein Refseq : NP_000558
MIM : 123260
UniProt ID : P02741
Chromosome Location : 1q21-q23
Function : Gram-positivebacterial cell surface binding; binding; cholesterol binding; cholinebinding; low-density lipoprotein particle binding; metal ion binding; proteinbinding; protein homodimerization activity

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