Recombinant Human Defensin, Beta 4A

• Cat.No.: DEFB4A-5190H
• Product Overview: Recombinant Human DEFB4Ais a protein containing 41 amino acid residues. DEFB4A is expressed in E. coli, MW 4.3kDa.

Specification

• Cat. No.: DEFB4A-5190H
• Description: Beta-defensin 2(DEFB4A) also known as skin-antimicrobial peptide 1 (SAP1) is a peptide thatin humans is encoded by the DEFB4A (defensin, beta 4) gene. Humanbeta-defensin-2 (DEFB4A) is a cysteine-rich cationic low molecular weightantimicrobial peptide recently discovered in lesional skin.
• Source: Human
• Host: E. coli
• Form: Sterile filtered andlyophilized with no additives.
• Purity: >98% by SDS-PAGEanalyses.
• Molecular Weight: 4.3 kDa
• Biological Activity: Determined by itsability to chemoattract immature dendritic cells using a concentration rangeof 10.0-100.0 ng/ml.
• Endotoxin Level: <.1 ng per µg
• Reconstitution: Centrifuge vialprior to opening. Reconstitute in water to a concentration of 0.1-1.0 mg/ml.This solution can then be diluted into other buffered solutions and stored at2-4°C for one week or at -20°C for future use.
• Storage: Store lyophilizedBD-2 desiccated below 0°C. Reconstituted BD-2 should be stored in workingaliquots at -20°C. Avoid repeated freeze-thaw cycles.
• OfficialSymbol: DEFB4A

Gene Information

• Gene Name: DEFB4A defensin, beta 4A [ Homosapiens ]
• Synonyms: DEFB4A;defensin, beta 4A; BD-2; SAP1; DEFB2; DEFB4; HBD-2; DEFB-2; DEFB102;beta-defensin 4A; defensin, beta 2; defensin, beta 4; OTTHUMP00000159651;skin-antimicrobial peptide 1; Defensin, beta 2; Skin-antimicrobial peptide 1;Beta-defensin 2; hBD-2
• Gene ID: 1673
• mRNA Refseq: NM_004942
• Protein Refseq: NP_004933
• MIM: 602215
• UniProt ID: O15263
• Chromosome Location: 8p23.1