| Cat. No. : |
FASLG-5412H |
| Product Overview : |
Recombinant Human soluble Fas Ligandcontains 175 amino acid residues and comprises the TNF homologous region ofFast plus an eight His-Tag. |
| Description : |
FASLG is a type-IItransmembrane protein that belongs to the tumor necrosis factor (TNF) family.Its binding with its receptor induces apoptosis. Fas ligand/receptorinteractions play an important role in the regulation of the immune systemand the progression of cancer. |
| Source : |
CHO cells |
| Species : |
Human |
| Form : |
Lyophilized withoutadditives. |
| Molecular Weight : |
17.9 kDa |
| Purity : |
<95% by RP-HPLC and SDS-PAGE. |
| Endotoxin Level : |
<0.1 ng/ug |
| Biological Activity : |
Determined by itsability to induce cytotoxicity in Jurkat cells in the absence of anycross-linking. The EDSO for this effect is <10.0 ng/ml. |
| Specific Activity : |
< 1 x 105units/mg |
| Reconstitution : |
Centrifuge vialprior to opening. First add sterile distilled water to the vial to fullysolubilize the protein to a concentration of 0.1-1.0 mg/ml. After completesolubilization of the protein, it can be further diluted to other aqueoussolutions. |
| Storage : |
Store lyophilizedprotein at -20°C and reconstituted protein in working aliquots at -20°C.Avoid repeated freeze-thaw cycles. |
| OfficialSymbol : |
FASLG |
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.