Recombinant Human Interleukin 5

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Recombinant Human Interleukin 5

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Cat. No. : IL5-1240H
Product Overview : Recombinant human IL5,produced in e. coli, is a non-glycosylated homodimer with each polypeptidechain containing 132 amino acids with a total MW 26.52284 kDa.
Description : The protein encoded by thisgene is a cytokine that acts as a growth and differentiation factor for bothB cells and eosinophils. This cytokine is a main regulator of eosinopoiesis,eosinophil maturation and activation. The elevated production of thiscytokine is reported to be related to asthma or hypereosinophilic syndromes.
Source : Escherichia Coli
Species : Human
Form : The protein waslyophilized from a concentrated (10mg/ml) solution with no additives.
Storage : Lyophilizedrecombinant human IL-5, although stable at room temperature, should be storeddesiccated below 0°C. Reconstituted recombinant human IL-5 is best storedrefrigerated at 4°C.
OfficialSymbol : IL5
Crystalstructure of human IL5 :

Gene Name : IL5 interleukin 5(colony-stimulating factor, eosinophil) [ Homo sapiens ]
Synonyms : IL5; interleukin 5(colony-stimulating factor, eosinophil); EDF; TRF; IL-5; interleukin-5;T-cell replacing factor; B cell differentiation factor I; eosinophildifferentiation factor; OTTHUMP00000065830; B-cell differentiation factor I
Gene ID : 3567
mRNA Refseq : NM_000879
Protein Refseq : NP_000870
MIM : 147850
UniProt ID : P05113
Chromosome Location : 5q31.1
Pathway : Allograft rejection; Asthma;Autoimmune thyroid disease; Cytokine-cytokine receptor interaction; Fcepsilon RI signaling pathway; Hematopoietic cell lineage; Jak-STAT signalingpathway; cell receptor signaling pathway
Function : cytokine activity; growthfactor activity; interleukin-4 receptor binding

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