Creative BioMart to Present at
                        BIO-Europe Spring Creative BioMart to Present at AACR Annual Meeting|Apr. 5-10, 2024|Booth #2953

Goat Anti-Human Hemoglobin PAb, HRP-Conjugation

Cat.No. : CPBTT30932GH
  • Specification
  • Gene Information
  • Related Products
Cat. No. : CPBTT30932GH
ProductOverview : Polyclonal Antibody to Hemoglobin(HRP), Involved in oxygen transport from the lung to the various peripheral tissues.
Antigen Description : Defects in HBA1/HBA2 may be a cause of Heinz body anemias. This is a form of non-spherocytic hemolytic anemia of Dacie type 1.The hemoglobin demonstrates heat lability. Heinz bodies are observed also with the Ivemark syndrome (asplenia with cardiovascular anomalies) and with glutathione peroxidase deficiency. The hallmark of alpha-thalassemia is an imbalance in globin-chain production in the adult HbA molecule. Due to the complete absence of alpha chains, the predominant fetal hemoglobin is a tetramer of gamma-chains (Bart hemoglobin) that has essentially no oxygen carrying capacity.
Immunogen : Human Hemoglobin.
Host animal : Goat
Cross reactivity : Human. Predicted to work with Rabbit, Dog, Chimpanzee, Rhesus monkey
Isotype : IgG
Conjugation : HRP
Conjugation notes : Molar enzyme/antibody protein ratio is 4:1.
Application : ICC; ELISA; WB
Storage Buffer : Preservative: 0.01% Thimerosal (merthiolate); Constituents: 0.1M Sodium chloride, 50mM HEPES. pH 7.1
Positive control : recombinant human hemoglobin
Specificity : The antibody has been tested in ELISA and IEP with a Human Hemaglobin Calibrator/Standard but has yet to be tested against endogenous protein.
Tissue Specificity : Red blood cells.
Sequence similarities : Belongs to the globin family.
Post-translationalmodifications : The initiator Met is not cleaved in variant Thionville and is acetylated
Purity : Immunogen affinity purified
Purification notes : Antibody concentration was determined by extinction coefficient prior to conjugation: absorbance at 280 nm of 1.4 equals 1.0 mg of IgG.
Storage : Store at +4°C.
Background :
IntroductionHemoglobin (also spelled haemoglobin and abbreviated Hb or Hgb) is the iron- containing oxygen-transport metalloprotein in the red blood cells of all vertebrates(with the exception of the fish family Channichthyidae) as well as the tissues of some invertebrates. Hemoglobin in the blood carries oxygen from the respiratory organs (lungs or gills) to the rest of the body (i.e. the tissues) where it releases the oxygen to burn nutrients to provide energy to power the functions of the organism, and collects the resultant carbon dioxide to bring it back to the respiratory organs to be dispensed from the organism.
KeywordsHemoglobin; Hb; Hgb; Alpha globin; Beta globin; CD113t C; CD31; Gamma 1 globin; Hb F Agamma; HBA 1; HBA 2; HBA; HBA_HUMAN; Alpha-globin; HBA1; HBA2; HBB; Hbb-y; HBD; Hbe1; HBG 1; HBG; HBG1; HBGA; HBGR; Hemoglobin alpha; Hemoglobin alpha chain; Hemoglobin alpha locus; Hemoglobin beta; Hemoglobin beta chain; Hemoglobin beta chain complex; Hemoglobin beta locus; Hemoglobin gamma 1 chain; Hemoglobin gamma A; Hemoglobin gamma A chain; Hemoglobin gamma; Hemoglobin subunit alpha; Hemoglobin subunit gamma 1; HSGGL1; MGC126895; PRO2979

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

Inquiry

  • Q&As
  • Reviews

Q&As (0)

Ask a question

Customer Reviews (0)

Write a review

Ask a Question for All Hb Products

Required fields are marked with *

My Review for All Hb Products

Required fields are marked with *

0

Inquiry Basket

cartIcon
logo

FOLLOW US

Terms and Conditions        Privacy Policy

Copyright © 2024 Creative BioMart. All Rights Reserved.

Contact Us

  • /

Stay Updated on the Latest Bioscience Trends