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Recombinant Human Ketohexokinase (fructokinase)

Cat. No.: KHK-905H
Product Overview: Ketohexokinase Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 298 amino acids and having a molecular mass of 32.7 kDa.
Description: Ketohexokinase catalyzes the phosphorylation of fructose to produce fructose-1-phosphate, resulting in the utilization of ATP and creation of AMP. Ketohexokinase commences initial step in the metabolism of dietary fructose and is a significant regulator of hepatic glucose metabolism. Ketohexokinase is found in liver, renal cortex, and small intestine.
Source: Human
Host: Escherichia Coli.
Form: The protein solution contains 1xPBS, pH 7.4 and 10 % glycerol.
Purity: Greater than 90.0 % as determined by SDS-PAGE.
Amino acid sequence: MEEKQILCVG LVVLDVISLV DKYPKEDSEI RCLSQRWQRG GNASNSCTIL SLLGAPCAFM GSMAPGHVAD FVLDDLRRYS VDLRYTVFQT TGSVPIATVI INEASGSRTI LYYDRSLPDV SATDFEKVDL TQFKWIHIEG RNASEQVKML QRIDAHNTRQ PPEQKIRVSV EVEKPREELF QLFGYGDVVF VSKDVAKHLG FQSAEEALRG LYGRVRKGAV LVCAWAEEGA DALGPDGKLL HSDAFPPPRV VDTLGAGDTF NASVIFSLSQ GRSVQEALRF GCQVAGKKCG LQGFDGIV
Storage: Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1 % HSA or BSA). Avoid multiple freeze-thaw cycles.
Gene Name: KHK ketohexokinase (fructokinase) [ Homo sapiens ]
Official Symbol: KHK
Synonyms: KHK; ketohexokinase (fructokinase); ketohexokinase; OTTHUMP00000122595; OTTHUMP00000122596; OTTHUMP00000200951; hepatic fructokinase
Gene ID: 3795
mRNA Refseq: NM_000221
Protein Refseq: NP_000212
MIM: 614058
UniProt ID: P50053
Chromosome Location: 2p23.3-p23.2
Pathway: Fructose and mannose metabolism; Fructose catabolism; Metabolic pathways; Metabolism of carbohydrates
Function: ATP binding; ketohexokinase activity; kinase activity; nucleotide binding; protein binding; transferase activity

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