||IL1B Human Recombinant produced in E.Coli is a single, non-glycosylated, His-Tag Polypeptide chain containing 153 amino acids fragment (117-269) and having a total molecular mass of 21.88 kDa with an amino-terminal hexahistidine tag. The IL-1B His is purified by proprietary chromatographic techniques.
||IL1B is a proinflammatory cytokine produced in a variety of cells including monocytes, tissue macrophages, keratinocytes and other epithelial cells. Both IL-1 alpha and IL1B binds to the same receptor and has similar if not identical biological properties. These cytokines have a broad range of activities including, stimulation of thymocyte proliferation, by inducing IL-2 release, B-cell maturation and proliferation, mitogenic FGF-like activity and the ability to stimulate the release of prostaglandin and collagenase from synovial cells. However, whereas IL1B is a secreted cytokine, IL-1 alpha is predominantly a cell-associated cytokine.
||IL1B His is supplied in 1μ PBS and 50% glycerol.
||Energy metabolism and body weight regulation
||Add deionized water to prepare a working stock solution of approximately 0.5 mg/mL and let the lyophilized pellet dissolve completely. Product is not sterile! Please filter the product by an appropriate sterile filter before using it in the cell culture.
||Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. Please avoid freeze thaw cycles.