"IL8" Related Products

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Recombinant Human IL8 (28-99aa)

Cat. No.: IL8-360H
Product Overview: Human IL8 (P10145, 28 a.a. - 99 a.a.) partial recombinant protein expressed in Escherichia coli.
Description: Interleukin-8 (IL8) is a chemokine produced by macrophages and other cell types such as epithelial cells. It is also synthesized by endothelial cells, which store IL8 in their storage vesicles, the Weibel-Palade bodies. In humans, the interleukin-8 protein is encoded by the IL8 gene.
Sequence: SAK ELRCQCIKTY SKPFHPKFIK ELRVIESGPH CANTEIIVKL SDGRELCLDP KENWVQRVVE KFLKRAENS
Theoretical MW (kDa): 8
Form: Lyophilized
Preparation Method: E. coli expression system
Purity: > 95% by SDS-PAGE and HPLC
Endotoxin Level: < 0.1 ng/ug (1 EU/ug)
Activity: Determined by its ability to chemoattract human peripheral blood neutrophils using a concentration range of 10.0-100.0 ng/mL.
Application: SDS-PAGE
Storage Buffer: Lyophilized from PBS, pH 7.5
Storage: Store at -20°C on dry atmosphere. After reconstitution with deionized water, store at -20°C. Aliquot to avoid repeated freezing and thawing.
Unitprot ID: P10145
Gene Name: IL8 interleukin 8 [ Homo sapiens ]
Official Symbol: IL8
Synonyms: IL8; 3-10C; AMCF-I; CXCL8; Emoctakin; GCP-1; GCP1; IL-8; K60; LECT; LUCT; LYNAP; MDNCF; MONAP; NAF; NAP-1; NAP1; SCYB8; TSG-1; b-ENAP; emoctakin; C-X-C motif chemokine 8; Granulocyte chemotactic protein 1; Monocyte-derived neutrophil chemotactic factor; Monocyte-derived neutrophil-activating peptide; Neutrophil-activating protein 1; Protein 3-10C; T cell chemotactic factor; T-cell chemotactic factor; beta-thromboglobulin-like protein; chemokine (C-X-C motif) ligand 8; interleukin 8; lymphocyte-derived neutrophil-activating factor; neutrophil-activating peptide 1; small inducible cytokine subfamily B, member 8; Interleukin-8
Gene ID: 3576
mRNA Refseq: NM_000584
Protein Refseq: NP_000575
MIM: 146930
Chromosome Location: 4q13-q21
Pathway: Cytokine-cytokine receptor interaction; Epithelial cell signaling in Helicobacter pylori infection; Leukocyte transendothelial migration; Toll-like receptor signaling pathway; Signaling by GPCR
Function: chemokine activity; interleukin-8 receptor binding; protein binding

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