"PRLR" Related Products

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Recombinant Human PRLP, GST-tagged

Cat. No.: PRLP-3704H
Product Overview: Cytoplasmatic PRLP Human Recombinant produced in E.coli is a non-glycosylated, Polypeptide chain amino acids 432-623 and having a molecular mass of 45 kDa, the PRLR is fused with a GST tag. PRLP is purified by proprietary chromatographic techniques.
Description: PRLP encoded by a gene on Chromosome 5p13-14 interacts with the prolactin molecule as a transmembrane receptor. Thus it contains an extracellular region that binds prolactin, a transmembrane regions, and a cytoplasmatic region. The receptor is a cytokine receptor, and the second messenger cascade is the JAK-STAT pathway. There may be variations among different tissue PRLP.
Source: E. coli
Species: Human
Form: PRLR Human at 0.1 mg/ml in 50 mM Tris-Acetate, pH 7.5, 1 mM EDTA and 20% Glycerol.
Research topic: Energy metabolism and body weight regulation
Applications: ELISA; Inhibition Assays; Western blotting
Storage: Store vial at -20°C to -80°C. When stored at the recommended temperature, this protein is stable for 12 months. Please prevent freeze-thaw cycles.
Gene Name: PRLR prolactin receptor [ Homo sapiens ]
Official Symbol: PRLR
Synonyms: PRLR; prolactin receptor; hPRLrI; PRL-R; hPRL receptor; OTTHUMP00000115998; OTTHUMP00000221070; OTTHUMP00000221071; OTTHUMP00000221073; secreted prolactin binding protein; delta 4-SF1b truncated prolactin receptor; delta 4-delta 7/11 truncated prolactin receptor
Gene ID: 5618
mRNA Refseq: NM_000949
Protein Refseq: NP_000940
MIM: 176761
UniProt ID: P16471
Chromosome Location: 5p14-p13
Pathway: Adipogenesis; Cytokine-cytokine receptor interaction; ErbB4 signaling events; Jak-STAT signaling pathway; Neuroactive ligand-receptor interaction; Ovarian Infertility Genes; Signaling events mediated by PTP1B
Function: cytokine receptor activity; metal ion binding; ornithine decarboxylase activator activity; peptide hormone binding; prolactin receptor activity; protein binding; protein homodimerization activity; receptor activity

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