||Cytoplasmatic PRLP Human Recombinant produced in E.coli is a non-glycosylated, Polypeptide chain amino acids 432-623 and having a molecular mass of 45 kDa, the PRLR is fused with a GST tag. PRLP is purified by proprietary chromatographic techniques.
||PRLP encoded by a gene on Chromosome 5p13-14 interacts with the prolactin molecule as a transmembrane receptor. Thus it contains an extracellular region that binds prolactin, a transmembrane regions, and a cytoplasmatic region. The receptor is a cytokine receptor, and the second messenger cascade is the JAK-STAT pathway. There may be variations among different tissue PRLP.
||PRLR Human at 0.1 mg/ml in 50 mM Tris-Acetate, pH 7.5, 1 mM EDTA and 20% Glycerol.
||Energy metabolism and body weight regulation
||ELISA; Inhibition Assays; Western blotting
||Store vial at -20°C to -80°C. When stored at the recommended temperature, this protein is stable for 12 months. Please prevent freeze-thaw cycles.