"HDAC1" Related Products

Expand
Expand

Recombinant Human Histone Deacetylase 1, GST-tagged

Cat. No.: HDAC1-1587H
Product Overview: Full-length recombinant human HDAC1 was expressed by baculovirus in Sf9 insect cells using a C-terminal GST tag.
Description: HDAC1 or Histone deacetylase 1 belongs to the histone deacetylase/acuc/apha family and is a component of the histone deacetylase complex which plays a key role in the regulation of eukaryotic gene expression. HDAC1 interacts with retinoblastoma tumor-suppressor protein and this complex is a key element in the control of cell proliferation and differentiation. Together with metastasis-associated protein-2, HDAC1 deacetylates p53 and modulates its effect on cell growth and apoptosis.
Applications: HDAC Assay; Western Blot
Molecular Weight: 88 kDa
Expression System: Sf9 insect cells using baculovirus
Species: Human
Form: Recombinant protein stored in 50 mM Tris-HCl, pH 7.5, 150 mM NaCl, 10 mM glutathione, 0.1 mM EDTA, 0.25 mM DTT, 0.1 mM PMSF, 25% glycerol.
Purity: >70%
Concentration: 0.1 ug/ul
Specific Activity: 8900 RLU/min/ng
Sequences: Full length
Storage: Store product at -70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
Pathways: Chronic myeloid leukemia; Delta-Notch Signaling Pathway; Delta-Notch Signaling Pathway; E2F transcription factor network; EGFR1 Signaling Pathway; Energy Metabolism; Hemostasis; Huntington"s disease; IL-6 Signaling Pathway; Pathways in cancer; Pathways in cancer; Regulation of Telomerase; Signalling by NGF; Signalling by NGF; TNF-alpha/NF-kB Signaling Pathway
Gene Name: HDAC1 histone deacetylase 1 [ Homo sapiens ]
Official Symbol: HDAC1
Synonyms: HDAC1; histone deacetylase 1; HD1; RPD3; GON-10; RPD3L1; DKFZp686H12203; histone deacetylase 1; OTTHUMP00000008745; reduced potassium dependency, yeast homolog-like 1
Gene ID: 3065
mRNA Refseq: NM_004964
Protein Refseq: NP_004955
MIM: 601241
UniProt ID: Q13547
Chromosome Location: 1p34
Function: NAD-dependent histone deacetylase activity (H3-K14 specific); NAD-dependent histone deacetylase activity (H3-K9 specific); RNA polymerase II transcription corepressor activity; RNA polymerase II transcription corepressor activity; activating transcription factor binding; enzyme binding; histone deacetylase activity; histone deacetylase activity (H3-K16 specific); histone deacetylase binding; hydrolase activity; protein binding; sequence-specific DNA binding transcription factor activity; transcription factor binding

Online Inquiry

Note: There will be extra charge for optional service!
Optional requirements on this protein    +Expand
C-fusion    N-fusion   Non-tagged
His    GST   Fc   Others
<1.0 eu/μg    <0.1 eu/μg   <0.01 eu/μg   Not required
Monomer Isolation    Dimer Isolation    Not required
>80% by SDS-PAGE    >90% by SDS-PAGE   >95% by SDS-PAGE   Others

Please input "biomart" as verification code. Please review Creative BioMart's privacy policy for more information


Price does not include shipping and packaging costs.Request quote for final price.

Price Inquiry

Welcome! For price inquiries, please feel free to contact us through the form below. We will get back to you as soon as possible.