Native Bovine IAP

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Native Bovine IAP

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Cat.No. : IAP-8323C
Product Overview : The Alkaline Phosphatase is purified by affinity chromatography, which results in an enzyme of high specific activity and purity.
Description : Alkaline Phosphatase is Dimeric protein having molecular weight of 140 kDa, one Zn++ ion is tightly bound to each subunit, and another less tightly bound is involved in the catalytic reaction. Mg++ stimulates the catalysis. The binding site for Mg++ is different to that of Zn++, but will be occupied by excess Zn++ followed by loss of enzyme activity.
Source : Calf
Species : Calf
Form : 50% glycerol, 5mM MgCl2, 0.1mM ZnCl2 and 5mM TRIS, pH 7.0.
Bio-activity : >1000 U/mg (pH 9.6, 25C and 0.025M glycin, 10% glycerol as buffer.
Purity : 95% pure by Gel Filtration.
Storage : AP should be stored at 4 °C. Please Do-Not freeze.
Gene Name : ALPI alkaline phosphatase, intestinal [ Bos taurus ]
Official Symbol : ALPI
Synonyms : IAP; intestinal-type alkaline phosphatase; intestinal alkaline phosphatase V
Gene ID : 280993
mRNA Refseq : NM_173987
Protein Refseq : NP_776412
Chromosome Location : 2q45
Pathway : Folate biosynthesis, organism-specific biosystem; Folate biosynthesis, conserved biosystem; tetrahydrofolate biosynthesis I mammals, organism-specific biosystem
Function : alkaline phosphatase activity; magnesium ion binding; zinc ion binding

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