ALPI
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Official Full Name
alkaline phosphatase, intestinal -
Overview
There are at least four distinct but related alkaline phosphatases: intestinal, placental, placental-like, and liver/bone/kidney (tissue non-specific). The intestinal alkaline phosphatase gene encodes a digestive brush-border enzyme. This enzyme is upregulated during small intestinal epithelial cell differentiation. -
Synonyms
ALPI;alkaline phosphatase, intestinal;IAP;intestinal-type alkaline phosphatase;intestinal alkaline phosphatase V
Recombinant Proteins
- Human
- Mouse
- Bovine
- Rat
- HEK293
- C-His
- Calf Intestine
- E.coli
- Wheat Germ
- Human Cells
- Yeast
- Mammalian Cells
- Bovine Intestine
- Bovine Intestinal Mucosa
- Fc
- His
- Flag
- Non
- GST
- DDK
- Myc
- Avi
- rFc
Involved Pathway
ALPI involved in several pathways and played different roles in them. We selected most pathways ALPI participated on our site, such as Folate biosynthesis,Metabolic pathways, which may be useful for your reference. Also, other proteins which involved in the same pathway with ALPI were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Metabolic pathways | FH1,RRM2B,NDUFAB1,ybaS,SEPHS2,ST6GAL2A,ACADL,GANAB,UPP2,PCXB |
| Folate biosynthesis | MOCS2,QDPRB1,FPGS,QDPRB2,PTS,MOCS1,SPR,GCH1,GCH2,QDPR |
Protein Function
ALPI has several biochemical functions, for example, alkaline phosphatase activity,magnesium ion binding,protease binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ALPI itself. We selected most functions ALPI had, and list some proteins which have the same functions with ALPI. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| alkaline phosphatase activity | ALPL,ALPI.1,ALPP,ALPPL2,ALP3 |
| zinc ion binding | DPP3,SREK1IP1,RNF26,ZDHHC19,LHX8A,ALAD,MYT1,BRD1,DPEP1,RNF43 |
| protein binding | HRAS,BCL7A,ADAM22,UBE2D2A,OLFM2,CAPN3,SLC6A18,PODXL2,DLC1,FIBPB |
| protease binding | ECM1,BRCA2,TNFRSF10A,SERPINA1E,SERPINB6,FLOT2,BDKRB2,COMP,TRP53,CCBE1 |
| magnesium ion binding | PGM3,STK36,RPS6KAL,IDH3B,FAN1,PRPSAP1,LATS1,ATP8B5,TSSK2,OPA1 |
Interacting Protein
ALPI has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ALPI here. Most of them are supplied by our site. Hope this information will be useful for your research of ALPI.
KRTAP10-8;KRTAP10-9;NOTCH2NL;EIF4A2;HSPB1;E2F3;Actb
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