Recombinant Human GCLM, His-tagged
Cat.No. : | GCLM-13195H |
Product Overview : | Recombinant Human GCLM protein, fused to His-tag, was expressed in E.coli and purified by Ni-sepharose. |
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- Gene Information
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Description : | This gene encodes a member of the TFB4 family. The encoded protein is a subunit of the core-TFIIH basal transcription factor and localizes to the nucleus. The encoded protein is involved in RNA transcription by RNA polymerase II and nucleotide excision repair and associates with the Cdk-activating kinase complex. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 14. |
Source : | E.coli |
Species : | Human |
Tag : | His |
Protein length : | 1-274a.a. |
Storage : | The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles. |
Storage Buffer : | 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 300mM Imidazole and 0.7% Sarcosyl, 15%glycerol. |
Gene Name : | GCLM glutamate-cysteine ligase, modifier subunit [ Homo sapiens ] |
Official Symbol : | GCLM |
Synonyms : | GCLM; glutamate-cysteine ligase, modifier subunit; GLCLR; glutamate--cysteine ligase regulatory subunit; gamma glutamylcysteine synthetase; GCS light chain; GSC light chain; gamma-ECS regulatory subunit; glutamate--cysteine ligase modifier subunit; glutamate-cysteine ligase regulatory protein; gamma-glutamylcysteine synthetase regulatory subunit; glutamate-cysteine ligase (gamma-glutamylcysteine synthetase), regulatory (30.8kD); |
Gene ID : | 2730 |
mRNA Refseq : | NM_002061 |
Protein Refseq : | NP_002052 |
MIM : | 601176 |
UniProt ID : | P48507 |
Chromosome Location : | 1p21 |
Pathway : | Biological oxidations, organism-specific biosystem; Glutathione biosynthesis, glutamate => glutathione, organism-specific biosystem; Glutathione biosynthesis, glutamate => glutathione, conserved biosystem; Glutathione conjugation, organism-specific biosystem; Glutathione metabolism, organism-specific biosystem; |
Function : | contributes_to glutamate-cysteine ligase activity; contributes_to glutamate-cysteine ligase activity; glutamate-cysteine ligase catalytic subunit binding; protein heterodimerization activity; |
Products Types
◆ Recombinant Protein | ||
GCLM-3508M | Recombinant Mouse GCLM Protein, His (Fc)-Avi-tagged | +Inquiry |
GCLM-4802H | Recombinant Human GCLM Protein, GST-tagged | +Inquiry |
GCLM-2149R | Recombinant Rat GCLM Protein, His (Fc)-Avi-tagged | +Inquiry |
Gclm-3175M | Recombinant Mouse Gclm Protein, Myc/DDK-tagged | +Inquiry |
GCLM-655H | Recombinant Human GCLM Protein, MYC/DDK-tagged | +Inquiry |
◆ Lysates | ||
GCLM-5982HCL | Recombinant Human GCLM 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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