Recombinant Human SPHK1, His-GST tagged
Cat.No. : | SPHK1-277H |
Product Overview : | Recombinant Human SPHK1 (Q9NYA1-1) (Met1-Leu384), fused with the N-terminal polyhistidine-tagged GST tag, was produced in Baculovirus-Insect cells. |
- Specification
- Gene Information
- Related Products
Source : | Baculovirus-Insect cells |
Species : | Human |
Tag : | His-GST |
Predicted N Terminal : | Met |
Form : | Lyophilized from sterile 20mM Tris, 500mM NaCl, 3mM DTT, 10% glycerol, pH 8.0.Normally 5 % - 8 % trehalose and mannitol are added as protectants before lyophilization. |
Molecular Mass : | The secreted recombinant human SPHK1 consists of 621 amino acids and predicts a molecular mass of 70.3 KDa. The apparent molecular mass of the protein is approximately 64 KDa in SDS-PAGE under reducing conditions due to glycosylation. |
Endotoxin : | < 1.0 eu per μg of the protein as determined by the LAL method. |
Purity : | >95 % as determined by SDS-PAGE |
Stability : | Samples are stable for up to twelve months from date of receipt at -70oC. |
Storage : | Store it under sterile conditions at -20oC~-70oC. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
Reconstitution : | It is recommended that sterile water be added to the vial to prepare a stock solution. Centrifuge the vial at 4℃ before opening to recover the entire contents. |
Gene Name : | SPHK1 sphingosine kinase 1 [ Homo sapiens ] |
Official Symbol : | SPHK1 |
Gene ID : | 8877 |
mRNA Refseq : | NM_001142601 |
Protein Refseq : | NP_001136073 |
MIM : | 603730 |
UniProt ID : | Q9NYA1 |
Chromosome Location : | 17q25.2 |
Products Types
◆ Recombinant Protein | ||
SPHK1-0268H | Recombinant Human SPHK1 Protein (M1-S363), His tagged | +Inquiry |
SPHK1-2567H | Recombinant Human SPHK1 Protein, MYC/DDK-tagged | +Inquiry |
SPHK1-091H | Recombinant Human SPHK1 Protein, His-tagged | +Inquiry |
SPHK1-012H | Recombinant Human SPHK1 Protein, His-tagged | +Inquiry |
SPHK1-5364R | Recombinant Rat SPHK1 Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
SPHK1-001HCL | Recombinant Human SPHK1 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
- Q&As
- Reviews
Q&As (5)
Ask a questionElevated SPHK1 levels have been associated with drug resistance in cancer cells, making it a potential target to overcome resistance mechanisms.
SPHK1 regulates immune cell trafficking and function by modulating S1P levels. This is significant in autoimmune diseases and inflammatory responses.
Understanding the role of SPHK1 in different diseases may contribute to the development of personalized therapeutic approaches, tailoring treatments based on individual patient characteristics and disease profiles.
SPHK1 is involved in endothelial cell functions and angiogenesis, making it a potential target in the treatment of vascular diseases.
Yes, combining SPHK1 inhibitors with other therapeutic agents is being explored to enhance treatment efficacy, especially in cancer.
Customer Reviews (3)
Write a reviewIts seamless integration makes it possible to explore different research avenues, expanding the scope and impact of my investigations.
With the manufacturer's excellent technical support and its wide range of applications, the SPHK1 protein has become an indispensable tool, aiding in my research endeavors and driving meaningful scientific discoveries.
Their team of experts is readily available to address any issues that may arise, providing solutions to problems and guiding me through the experimental process.
Ask a Question for All SPHK1 Products
Required fields are marked with *
My Review for All SPHK1 Products
Required fields are marked with *
Inquiry Basket