Active Native Porcine Kidney Alkaline Phosphatase
Cat.No. : | ALP-151P |
Product Overview : | Purified native Porcine Kidney Alkaline Phosphatase. CAS Number: 9001-78-9; E.C. Number: 3.1.3.1 |
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Description : | Alkaline Phosphatase is a hydrolase enzyme responsible for removing phosphate groups in the 5- and 3- positions from many types of molecules, including nucleotides, proteins, and alkaloids. In humans, alkaline phosphatase is present in all tissues throughout the entire body, but is particularly concentrated in liver, bile duct, kidney, bone, and the placenta. The optimal pH for the enzyme activity is 10.0 in standard conditions |
Source : | Porcine Kidney |
Species : | Porcine |
Form : | Lyophilized from tris chloride |
Bio-activity : | >100 U/mg protein |
Purity : | >95% (SDS-PAGE) |
Unit Definition : | One unit catalyzes the hydrolysis of one micromole of p-nitrophenyl phosphate per minute at 37C and pH 10.35 in the presence of 2-amino-2-methyl-1-propanol. |
Storage : | 2-8 centigrade. |
Concentration : | >0.5 mg/mg (Coomassie) |
Products Types
◆ Native Protein | ||
ALP-8330C | Native Calf ALP | +Inquiry |
◆ Assay kits | ||
Kit-0078 | Alkaline Phosphatase Colorimetric Assay Kit | +Inquiry |
Kit-0865 | Alkaline Phosphatase Fluorometric Assay Kit (Near Infrared) | +Inquiry |
Kit-0080 | Alkaline Phosphatase Fluorometric Assay Kit | +Inquiry |
Kit-0079 | Alkaline Phosphatase Assay Kit | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (13)
Ask a questionA comprehensive examination, such as liver function and bone densitometry, is usually required to determine the specific cause.
ALP mainly exists in the skeletal system, so bone diseases can lead to increased ALP, such as osteoporosis and bone metastatic cancer.
Elevated ALP is only one indicator, and its significance varies in different circumstances, but it does not necessarily mean that there is a serious disease that requires further diagnosis.
Obstruction of the biliary tract leads to cholestasis, which in turn leads to an increased ability of the liver to synthesize ALP, so ALP is elevated.
Disease-specific treatments are needed to effectively reduce ALP levels.
There is no significant association between elevated ALP and AIDS.
Elevated ALP itself does not require treatment, but if there is an underlying disease, it does.
ALP testing is usually done by drawing blood.
When ALP is elevated, patients usually experience fatigue, loss of appetite, abdominal pain, jaundice and other symptoms.
The liver is mainly responsible for the synthesis and release of ALP, so liver diseases can lead to elevated ALP, such as hepatitis and cirrhosis.
Elevated ALP by itself does not lead to complications, but if there is an underlying condition, untreated may lead to related complications.
When the above related symptoms occur, an ALP test is required.
When ALP is elevated, it is important to avoid eating high-fat foods and drinking alcohol.
Customer Reviews (4)
Write a reviewStability of ALP means that we can easily store it and use it at any time without worrying about its performance degradation.
The purity is high, showing good control of the production process.
This repeatability is good, which can reduce the error in the experiment and improve the repeatability of the experiment.
ALP showed excellent performance in Western blot and did not affect its performance even when stored for a long time.
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