"NEUROG3" Related Products

Recombinant Human neurogenin 3, His-tagged

Cat.No.: NEUROG3-401H
Product Overview: NEUROG3, 1-214aa, Human, His tag, E.coli
Description: NEUROG3 is a basic helix-loop-helix (bHLH) transcription factor involved in neurogenesis. The protein likely acts as a heterodimer with another bHLH protein. Defects in this gene are a cause of congenital malabsorptive diarrhea 4 (DIAR4). Recombinant human NeuroG3 protein, fused to His-tag at N-terminus, was expressed in E.coli
Source: E.coli
Species: Human
Tag: His-tag
Form: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 10% glycerol, 0.4M Urea
Molecular Mass: 25.1 kDa (234aa)
AA Sequence: MGSSHHHHHH SSGLVPRGSH MTPQPSGAPT VQVTRETERS FPRASEDEVT CPTSAPPSPT RTRGNCAEAE EGGCRGAPRK LRARRGGRSR PKSELALSKQ RRSRRKKAND RERNRMHNLN SALDALRGVL PTFPDDAKLT KIETLRFAHN YIWALTQTLR IADHSLYALE PPAPHCGELG SPGGSPGDWG SLYSPVSQAG SLSPAASLEE RPGLLGATSS ACLSPGSLAF SDFL
Purity: >85% by SDS - PAGE
Storage: Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
Concentration: 0.25 mg/ml (determined by Bradford assay)
Gene Name: NEUROG3 neurogenin 3 [ Homo sapiens ]
Official Symbol: NEUROG3
Synonyms: NEUROG3; neurogenin 3; neurogenin-3; Atoh5; bHLHa7; Math4B; ngn3; protein atonal homolog 5; class A basic helix-loop-helix protein 7; NGN-3;
Gene ID: 50674
mRNA Refseq: NM_020999
Protein Refseq: NP_066279
MIM: 604882
UniProt ID: Q9Y4Z2
Chromosome Location: 10q21.3
Pathway: Developmental Biology, organism-specific biosystem; Maturity onset diabetes of the young, organism-specific biosystem; Maturity onset diabetes of the young, conserved biosystem; Notch-mediated HES/HEY network, organism-specific biosystem; Regulation of beta-cell development, organism-specific biosystem; Regulation of gene expression in endocrine-committed (NEUROG3+) progenitor cells, organism-specific biosystem; Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells, organism-specific biosystem;
Function: DNA binding; double-stranded DNA binding; transcription coactivator activity;

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