Recombinant Bovine IL-4

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Recombinant Bovine IL-4

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Cat.No. : IL4-18B
Product Overview : Bovine IL-4 was produced in yeast and therefore does not have endotoxin, is naturally folded, and post-translationally modified.
Description : Interleukin-4 (IL-4) induces differentiation of naive helper T cells (Th0 cells) to Th2 cells. Upon activation by IL-4, Th2 cells subsequently produce additional IL-4. IL-4 has many biological roles, including the stimulation of activated B-cell and T-cell proliferation, and the differentiation of CD4+ T-cells into Th2 cells. It is a key regulator in humoral and adaptive immunity. IL-4 induces B-cell class switching to IgE, and up-regulates MHC class II production. Overproduction of IL-4 is associated with allergies.
Source : Yeast
Species : Bovine
Form : Lyophilized
Bio-activity : The biological activity of recombinant bovine IL-4 was measured in a cell proliferation assay using the human TF-1 cell line. The ED50 for this effect is typically 1.5 - 2 ng/mL.
Molecular Mass : 12.6 kDa
AA Sequence : GHKCDIT LAEIIKTLNI LTTRKNSCME LPVADVFAAP KNTTEKETFC RVGIELRRIY RSHTCLNKFL GGLDRNLNSL ASKTCSVNEA KTSTSTLKDL LERLKTIMKE KYSKC
Applications : The Bovine IL-4 protein can be used in cell culture, as an IL-4 ELISA Standard, and as a Western Blot Control.
Storage : -20 C
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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