Cat.No.:	CX3CL1-281H
Product Overview:	The extracellular domain of human CX3CL1 (AAH01163.1) (Gln25-Gly100) is fused to the N-terminus of the Fc region of mouse IgG2a was expressed in CHO celL
Description:	CX3CL1 (chemokine (C-X3-C motif) ligand 1) is a protein-coding gene. Diseases associated with CX3CL1 include pityriasis rosea, and rheumatoid vasculitis, and among its related super-pathways are MIF Mediated Glucocorticoid Regulation and Chemokine signaling pathway. GO annotations related to this gene include chemokine activity and receptor binding.
Source:	CHO cells
Species:	Human
Tag:	MIgG2a Fc-tagged
Form:	Lyophilized from 0.2μm-filtered solution in PBS.
Bio-activity:	Measured by its ability to chemoattract BaF3 mouse pro-B cells transfected with mouse CX3CR1.
Molecular Mass:	35 KDa (monomer)
AA Sequence:	Gln25-Gly100
Endotoxin:	<0.06 eu/μg as determined by lal test.>
Purity:	>98%, by SDS-PAGE under reducing conditions.
Stability:	Stable for at least 1 year after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C.
Reconstitution:	Reconstitute at 100μg/ml in sterile PBS.
Warning:	Avoid freeze/thaw cycles.

Gene Name:	CX3CL1 chemokine (C-X3-C motif) ligand 1 [ Homo sapiens ]
Official Symbol:	CX3CL1
Synonyms:	CX3CL1; chemokine (C-X3-C motif) ligand 1; SCYD1, small inducible cytokine subfamily D (Cys X3 Cys), member 1 (fractalkine, neurotactin); fractalkine; ABCD 3; C3Xkine; CXC3; CXC3C; neurotactin; NTN; C-X3-C motif chemokine 1; small-inducible cytokine D1; CX3C membrane-anchored chemokine; small inducible cytokine subfamily D (Cys-X3-Cys), member-1; small inducible cytokine subfamily D (Cys-X3-Cys), member 1 (fractalkine, neurotactin); NTT; SCYD1; ABCD-3;
Gene ID:	6376
mRNA Refseq:	NM_002996
Protein Refseq:	NP_002987
MIM:	601880
UniProt ID:	P78423
Chromosome Location:	16q13
Pathway:	Chemokine receptors bind chemokines, organism-specific biosystem; Chemokine signaling pathway, organism-specific biosystem; Chemokine signaling pathway, conserved biosystem; Class A/1 (Rhodopsin-like receptors), organism-specific biosystem; Cytokine-cytokine receptor interaction, organism-specific biosystem; Cytokine-cytokine receptor interaction, conserved biosystem; Direct p53 effectors, organism-specific biosystem;
Function:	chemokine activity; protein binding; receptor binding;

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