Active Recombinant Rat Chemokine (C-X3-C motif) Ligand 1
Cat.No. : | Cx3cl1-460R |
Product Overview : | Recombinant Rat Cx3cl1protein was expressed in Sf21. Gln25-Thr334. |
- Specification
- Gene Information
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Cat. No. : | Cx3cl1-460R |
Description : | Cx3cl1, also named neurotactin, is a member of the delta chemokinesubfamily that contains a novel C-X3-C motif. Unlike other known chemokines, Cx3cl1 is a type 1 membrane protein containing a chemokine domaintethered on a long mucinlike stalk. Rat Cx3cl1cDNA encodes a 393 amino acid (aa) residue precursor protein with two alternative(21 aa or 24 aa residue) putative signal peptides, a 76 aa residue globular chemokinedomain, a 238 aa residue stalk region rich in Gly, Pro, Ser and Thr and containingdegenerate mucinlike repeats, a 19 aa residue transmembrane segment and a 36 aaresidue cytoplasmic domain. |
Source : | Spodoptera frugiperda,Sf 21 (baculovirus) |
Form : | Lyophilized from a 0.2μm filtered solution in PBS with BSA as a carrier protein. |
N-terminalSequence : | No results obtained:Gln25 predicted |
Molecular Weight : | 33 kDa |
Activity : | Measuredby its ability to chemoattract mouse Cx3cl1 transfected BaF3 mouse proB cells. The ED50 forthis effect is typically 0.02-0.08 ng/mL. |
Endotoxin Level : | <1.0 EUper 1 μg of the protein by the LAL method. |
Purity : | >97%,by SDS-PAGE under reducing conditions and visualized by silver stain. |
Reconstitution : | Reconstituteat 100 μg/mL in sterile PBS that containing at least 0.1% human or bovine serumalbumin. |
Storage : | Use a manualdefrost freezer and avoid repeated freezethaw cycles. 12 months from date of receipt, -20 to -70°C as supplied.1 month, 2 to 8°C under sterile conditions after reconstitution. 3 months,-20 to -70°C under sterile conditions after reconstitution. |
Gene Name : | Cx3cl1 chemokine(C-X3-C motif) ligand 1 [ Rattus norvegicus ] |
Official Symbol : | Cx3cl1 |
Synonyms : | Cx3cl1; chemokine(C-X3-C motif) ligand 1; Cx3c; Scyd1; fractalkine; neurotactin; C-X3-C motif chemokine1; small-inducible cytokine D1; CX3C membrane-anchored chemokine; small induciblecytokine subfamily D, 1; Acc1; Fkn |
Gene ID : | 89808 |
mRNA Refseq : | NM_134455 |
Protein Refseq : | NP_604450 |
UniProt ID : | O55145 |
Chromosome Location : | 19p12 |
Pathway : | Chemokine receptors bindchemokines; Chemokine signaling pathway; Class A/1 (Rhodopsin-like receptors);Cytokine-cytokine receptor interaction; GPCR ligand binding; Peptide ligand-bindingreceptors; Signal Transduction; Signaling by GPCR |
Function : | chemokine activity |
Products Types
◆ Recombinant Protein | ||
CX3CL1-283C | Active Recombinant Human CX3CL1 Protein (315 aa) | +Inquiry |
Cx3cl1-189C | Active Recombinant Rat Cx3cl1 Protein (310 aa) | +Inquiry |
CX3CL1-926C | Recombinant Canine CX3CL1 Protein (Met1-Gly100), His-tagged | +Inquiry |
CX3CL1-482H | Recombinant Human CX3CL1 Protein | +Inquiry |
Cx3cl1-2385M | Active Recombinant Mouse Cx3cl1 Protein | +Inquiry |
◆ Lysates | ||
CX3CL1-840CCL | Recombinant Canine CX3CL1 cell lysate | +Inquiry |
CX3CL1-3019HCL | Recombinant Human CX3CL1 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (5)
Ask a questionCX3CL1 is involved in pain modulation, and its dysregulation is associated with neuropathic pain conditions. Understanding its role may lead to the development of novel analgesic therapies.
Yes, several clinical trials are investigating the therapeutic potential of targeting CX3CL1 in various diseases, including cancer, neurodegenerative disorders, and cardiovascular diseases.
CX3CL1 contributes to inflammation in cardiovascular diseases and affects vascular function. Studying its role helps in understanding the pathophysiology of conditions like atherosclerosis.
CX3CL1 acts as a chemoattractant, facilitating the recruitment and activation of immune cells at the site of inflammation, playing a pivotal role in immune response regulation.
Researchers are exploring CX3CL1 as a potential biomarker for diseases such as rheumatoid arthritis and certain cancers, aiming to develop diagnostic tools and monitor disease progression.
Customer Reviews (3)
Write a reviewthe CX3CL1 protein's compatibility with various experimental techniques further supports its usability.
One of the standout features of the CX3CL1 protein is the excellent technical support provided by the manufacturer.
Whether I need to study protein-protein interactions, protein localization, or protein folding, the CX3CL1 protein consistently delivers precise and meaningful data.
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