CX3CL1

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CX3CL1

Official Full Name chemokine (C-X3-C motif) ligand 1
Background The soluble form is chemotactic for T-cells and monocytes, but not for neutrophils. The membrane-bound form promotes adhesion of those leukocytes to endothelial cells. May play a role in regulating leukocyte adhesion and migration processes at the endothelium. Binds to CX3CR1.
Synonyms CX3CL1; chemokine (C-X3-C motif) ligand 1; NTN; NTT; CXC3; CXC3C; SCYD1; ABCD-3; C3Xkine; fractalkine; neurotactin; fractalkine; C-X3-C motif chemokine 1; small-inducible cytokine D1; CX3C membrane-anchored chemokine; small inducible cytokine subfamily D (Cys-X3-Cys), member-1; small inducible cytokine subfamily D (Cys-X3-Cys), member 1 (fractalkine, neurotactin);
    • Species :
    • Bovine
    • Canine
    • Chicken
    • Cynomolgus
    • Cynomolgus Monkey
    • Human
    • Mouse
    • Rat
    • Rhesus Macaque
    • Source :
    • CHO
    • E. coli
    • E.coli
    • HEK293
    • HEK293 cells
    • Human Cell
    • Human Cells
    • Mammalian Cell
    • Mammalian cells
    • Sf21 Insect Cell
    • Spodoptera Frugiperda
    • Wheat Germ
    • Yeast
    • Tag :
    • Biotin
    • Fc
    • Flag
    • GST
    • His
    • His/Avi
    • T7
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human CX3CL1-051H Recombinant Human CX3CL1 protein, His/Avi-tagged, Biotinylated HEK293 cells His/Avi
    Human CX3CL1-278H Recombinant Human CX3CL1 Protein, His-tagged Human Cells His
    Human CX3CL1-039H Recombinant Human CX3CL1 Protein HEK293 N/A
    Human CX3CL1-103H Human CX3CL1, Biotin-tagged Biotin
    Human CX3CL1-114H Recombinant Human chemokine (C-X3-C motif) ligand 1, His-tagged E.coli His
    Human CX3CL1-11712H Recombinant Human CX3CL1, GST-tagged E.coli GST
    Human CX3CL1-123H Recombinant Human Chemokine (C-X3-C Motif) Ligand 1 Mammalian cells N/A
    Human CX3CL1-209H Recombinant Human CX3CL1, Fc-tagged CHO Fc
    Human CX3CL1-2147H Recombinant Human CX3CL1 Protein, GST-tagged Wheat Germ GST
    Human CX3CL1-223H Recombinant Human CX3CL1 protein E.coli N/A
    Human CX3CL1-27741TH Recombinant Human CX3CL1 protein, FLAG-tagged HEK293 Flag
    Human CX3CL1-28053TH Recombinant Human CX3CL1, His-tagged E.coli His
    Human CX3CL1-28060TH Recombinant Human CX3CL1 E.coli Fc
    Human CX3CL1-281H Recombinant Human CX3CL1, MIgG2a Fc-tagged CHO Fc
    Human CX3CL1-286H Recombinant Human CX3CL1, HIgG1 Fc-tagged CHO Fc
    Human CX3CL1-3019HCL Recombinant Human CX3CL1 cell lysate Human Cell N/A
    Human CX3CL1-399H Recombinant Human CX3CL1 protein, His-tagged HEK293 His
    Human CX3CL1-765H Recombinant Human CX3CL1 protein, His-tagged E.coli His
    Human CX3CL1-766H Recombinant Human CX3CL1 protein, His & T7-tagged E.coli His/T7
    Human CX3CL1-86H Recombinant Human CX3CL1, His tagged Human Cell His
    Human CX3CL1-87H Recombinant Human CX3CL1 Protein, His-tagged, Biotinylated HEK293 His
    Mouse Cx3cl1-127M Recombinant Mouse Chemokine (C-X3-C Motif) Ligand 1 Sf21 Insect Cell N/A
    Mouse Cx3cl1-225M Recombinant Mouse Cx3cl1 E.coli N/A
    Mouse Cx3cl1-2385M Recombinant Mouse Cx3cl1 Protein E. coli
    Mouse Cx3cl1-345M Recombinant Mouse Cx3cl1 Protein, His-tagged Yeast His
    Mouse Cx3cl1-379M Recombinant Mouse Chemokine (C-X3-C motif) Ligand 1 E.coli N/A
    Mouse Cx3cl1-380M Recombinant Mouse Chemokine (C-X3-C motif) Ligand 1, His-tagged Spodoptera Frugiperda His
    Mouse CX3CL1-4094M Recombinant Mouse CX3CL1 Protein Mammalian Cell His
    Mouse Cx3cl1-767M Recombinant Mouse Cx3cl1 protein, His-tagged E.coli His
    Mouse Cx3cl1-949M Recombinant Mouse Cx3cl1 protein E.coli N/A
    Mouse Cx3cl1-950M Recombinant Mouse Cx3cl1 E.coli N/A
    Mouse Cx3cl1-951M Recombinant Mouse Cx3cl1 Protein, His-tagged Sf21 Insect Cell His
    Rat Cx3cl1-128R Recombinant Rat Cx3cl1 Chemokine (C-X3-C Motif) Ligand 1 Sf21 Insect Cell N/A
    Rat CX3CL1-1683R Recombinant Rat CX3CL1 Protein Mammalian Cell His
    Rat Cx3cl1-460R Recombinant Rat Chemokine (C-X3-C motif) Ligand 1 Spodoptera Frugiperda N/A
    Rat Cx3cl1-633R Recombinant Rat Cx3cl1 protein E.coli N/A
    Rat Cx3cl1-768R Recombinant Rat Cx3cl1 protein, His-tagged E.coli His
    Rat Cx3cl1-992R Recombinant Rat Cx3cl1 Sf21 Insect Cell N/A
    Cynomolgus Monkey CX3CL1-187C Recombinant Cynomolgus CX3CL1, Fc-tagged Human Cell Fc
    Cynomolgus CX3CL1-344C Recombinant Cynomolgus Fractalkine Protein, His-tagged HEK293 His
    Rhesus Macaque CX3CL1-1102R Recombinant Rhesus monkey CX3CL1 Protein, His-tagged Mammalian Cell His
    Canine CX3CL1-176C Recombinant Canine CX3CL1, LEVLFQ tagged Human Cell Fc
    Canine CX3CL1-177C Recombinant Canine CX3CL1, Fc tagged Human Cell Fc
    Canine CX3CL1-840CCL Recombinant Canine CX3CL1 cell lysate Human Cell N/A
    Canine CX3CL1-926C Recombinant Canine CX3CL1 Protein (Met1-Gly100), His-tagged HEK293 His
    Bovine CX3CL1-4319B Recombinant Bovine CX3CL1 Protein Yeast N/A
    Chicken CX3CL1-3510C Recombinant Chicken CX3CL1 Mammalian Cell His

    CX3CL1 involved in several pathways and played different roles in them. We selected most pathways CX3CL1 participated on our site, such as Cytokine-cytokine receptor interaction, Chemokine signaling pathway, TNF signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with CX3CL1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Cytokine-cytokine receptor interaction Flt3l; CXCR3; IL5; EDAR; CSH; IL11; GHR; IFNG1-2; IL23; CCL8
    Chemokine signaling pathway GRK5; Adcy4; PF4V1; GNG10; CCL24; CCL23; PRKACB; CCL14; CCL28; STAT1
    TNF signaling pathway MAP3K5; BIRC3; TRAF2; TRAF5; CREB3L1; RPS6KA5; CCL5; ITCH; Casp3; TNF

    CX3CL1 has several biochemical functions, for example, CCR chemokine receptor binding, chemokine activity, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CX3CL1 itself. We selected most functions CX3CL1 had, and list some proteins which have the same functions with CX3CL1. You can find most of the proteins on our site.

    Function Related Protein
    CCR chemokine receptor binding CCL20A.3; CCL44; CX3CL1; XCL1; CCL8; CCL18; CCL17; CCL19; CCL3L1; CXCL32B.1
    chemokine activity CXCL11; Ccl21a; CCL1; CX3CL1; CXCL12A; Cxcl15; CXCL6; CCL21B; PF4V1; CCL2
    protein binding SYTL4; NAA30; MOBP; ERC1; THOC1; UNC45A; FASTKD3; EID3; POGK; TMEM183A
    receptor binding GLA; PPY; GSDMA2; PLXNC1; LEPROT; IL29; VTCN1; GRIN2A; HTT; PVRL1

    CX3CL1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CX3CL1 here. Most of them are supplied by our site. Hope this information will be useful for your research of CX3CL1.

    Herbst, RS; Soria, JC; et al. Predictive correlates of response to the anti-PD-L1 antibody MPDL3280A in cancer patients. NATURE 515:563-+(2014).
    Salvador, R; Aridgides, D; et al. Parasite-Derived Neurotrophic Factor/trans-Sialidase of Trypanosoma cruzi Links Neurotrophic Signaling to Cardiac Innate Immune Response. INFECTION AND IMMUNITY 82:3687-3696(2014).

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