Recombinant Human S-adenosyl-L-homocysteine hydrolase AHCY-2H

Cat.No.:	AHCY-2H
Description:	S-adenosylhomocysteine hydrolase belongs to the adenosylhomocysteinase family. It catalyzes the reversible hydrolysis of S-adenosylhomocysteine (AdoHcy) to adenosine (Ado) and L-homocysteine (Hcy). Thus, it regulates the intracellular S-adenosylhomocysteine (SAH) concentration thought to be important for transmethylation reactions. Deficiency in this protein is one of the different causes of hypermethioninemia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Species:	Human
Form:	Liquid
Purity:	Greater than 90% as determined by Analysis by SDS-PAGE.
Usage:	This product as supplied is intended forresearch use only, not for use in human, therapeutic or diagnostic applications.
Storage Buffer:	20 mM Tris pH 7.5, 20% glycerol, 1‰NaN3

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Gene Name:	AHCY adenosylhomocysteinase [ Homo sapiens ]
Official Symbol:	AHCY
Synonyms:	AHCY; adenosylhomocysteinase; S adenosylhomocysteine hydrolase; SAHH; adoHcyase; S-adenosylhomocysteine hydrolase; S-adenosyl-L-homocysteine hydrolase;
Gene ID:	191
mRNA Refseq:	NM_000687
Protein Refseq:	NP_000678
MIM:	180960
UniProt ID:	P23526
Chromosome Location:	20q11.22
Pathway:	Biological oxidations, organism-specific biosystem; Cysteine and methionine metabolism, organism-specific biosystem; Cysteine and methionine metabolism, conserved biosystem; Metabolic pathways, organism-specific biosystem; Metabolism, organism-specific biosystem; Metabolism of amino acids and derivatives, organism-specific biosystem; Methionine degradation, organism-specific biosystem;
Function:	adenosylhomocysteinase activity; hydrolase activity;