"FGFR3" Related Products

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Recombinant Human FGFR3, Fc Chimera

Cat.No.: FGFR3-700H
Product Overview: Recombinant Human FGFR3 (Accession # NP_001156685) was produced in Mouse myeloma cell line, NS0-derived.
Source: NSO cells
Species: Human
Tag: Fc Chimera
Predicted N Terminal: Glu23
Form: Lyophilized from a 0.2 µm filtered solution in PBS.
Bio-activity: Measured by its ability to inhibit FGF acidic-dependent proliferation of NR6R-3T3 mouse fibroblast cells.The ED50 for this effect is typically 0.03 - 0.12 µg/mL.
Molecular Mass: Recombinant Human FGFR3, Fc Chimera has a calculated MW of 65 kDa (monomer). In SDS-PAGE migrates as 90-100 kDa, reducing conditions.
Purity: >90%, by SDS-PAGE under reducing conditions and visualized by silver stain.
Storage: Avoid repeated freeze-thaw cycles. No activity loss was observed after storage at: In lyophilized state for 1 year (4ºC); After reconstitution under sterile conditions for 3 months (-70ºC).
Gene Name: FGFR3 fibroblast growth factor receptor 3 [ Homo sapiens ]
Official Symbol: FGFR3
Synonyms: FGFR3; fibroblast growth factor receptor 3; ACH, achondroplasia, thanatophoric dwarfism; CD333; CEK2; JTK4; FGFR-3; tyrosine kinase JTK4; hydroxyaryl-protein kinase; ACH; HSFGFR3EX;
Gene ID: 2261
mRNA Refseq: NM_000142
Protein Refseq: NP_000133
MIM: 134934
UniProt ID: P22607
Chromosome Location: 4p16.3

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