Recombinant Human GDF11 GDF11-1078H

Recombinant Human GDF11

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Recombinant Human GDF11

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Cat.No. : GDF11-1078H
Product Overview : Recombinant Human GDF11 (Accession # O95390) Asn299-Ser407, fused with an N-terminal Met, was produced in E. coli.
Source : E. coli
Species : Human
Predicted N Terminal : Met-Asn299-Leu-Gly-Leu-Asp-(Cys)-Asp-Glu-His
Form : Lyophilized from a 0.2 μm filtered solution in Acetonitrile and TFA with BSA as a carrier protein.
Bio-activity : Measured by its ability to induce hemoglobin expression in K562 human chronic myelogenous leukemia cells. Schwall, R.H. et al. (1991) Method Enzymol. 198:340. The ED50
Molecular Mass : Recombinant Human GDF11, Met-tagged has a calculated MW of 12.6 kDa. In SDS-PAGE migrates as 13 kDa, reducing conditions.
Protein length : Asn299-Ser407
Purity : Assessed by mass spectrometry, and is >95% pure by SDS-PAGE under reducing conditions visualized by silver stain (see below).
Storage : Avoid repeated freeze-thaw cycles. No activity loss was observed after storage at: In lyophilized state for 1 year (4ºC); After reconstitution under sterile conditions for 3 months (-70ºC).
Reconstitution : Reconstitute at 100 µg/mL in 4 mM HCl containing at least 0.1% human or bovine serum albumin.
Gene Name : GDF11 growth differentiation factor 11 [ Homo sapiens ]
Official Symbol : GDF11
Synonyms : GDF11; growth differentiation factor 11; growth/differentiation factor 11; BMP 11; GDF-11; bone morphogenetic protein 11; BMP11; BMP-11;
Gene ID : 10220
mRNA Refseq : NM_005811
Protein Refseq : NP_005802
MIM : 603936
UniProt ID : O95390
Chromosome Location : 12q13.13

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