Recombinant Human PPP1R15A protein, MYC/DDK-tagged

• Cat.No.: PPP1R15A-2943H
• Product Overview: Recombinant Human PPP1R15A, fussed with MYC/DDK tag at C-terminal, was expressed in HEK293 cells.

Specification

• Description: This gene is a member of a group of genes whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents. The induction of this gene by ionizing radiation occurs in certain cell lines regardless of p53 status, and its protein response is correlated with apoptosis following ionizing radiation.
• Source: HEK293
• Species: Human
• Tag: MYC/DDK
• Form: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 73.3 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Notes: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
• Concentration: >50 ug/mL as determined by microplate BCA method

Gene Information

• Gene Name: PPP1R15A protein phosphatase 1, regulatory subunit 15A [ Homo sapiens ]
• Official Symbol: PPP1R15A
• Synonyms: PPP1R15A; protein phosphatase 1, regulatory subunit 15A; protein phosphatase 1, regulatory (inhibitor) subunit 15A; protein phosphatase 1 regulatory subunit 15A; GADD34; growth arrest and DNA damage inducible 34; growth arrest and DNA-damage-inducible 34; growth arrest and DNA damage-inducible protein GADD34; myeloid differentiation primary response protein MyD116 homolog
• Gene ID: 23645
• mRNA Refseq: NM_014330
• Protein Refseq: NP_055145
• MIM: 611048
• UniProt ID: O75807
• Chromosome Location: 19q13.2
• Pathway: BMP receptor signaling, organism-specific biosystem; Protein processing in endoplasmic reticulum, organism-specific biosystem; Protein processing in endoplasmic reticulum, conserved biosystem; TGF-beta receptor signaling, organism-specific biosystem
• Function: protein binding