Recombinant Murine Interleukin 12b
Cat.No. : | Il12b-178M |
Product Overview : | Recombinant Murine Interleukin 12b produced inCHOwas a 40.0kDa protein containing 313 amino acid residues. |
- Specification
- Gene Information
- Related Products
Cat. No. : | Il12b-178M |
Description : | Interleukin-12 is a disulfide-linked heterodimeric protein (p70), composed of two subunits, p35 and p40, which are encoded by two different genes. Accumulating data indicate that p40 secretion precedes that of IL-12 expression. In addition, to its ability to covalently bind to p35 to form IL-12, p40 can bind to p19 to form IL-23. Additionally, p40 can associate itself through disulfide linkage to form a dimer that acts as a potent IL12 antagonist. |
Source : | E.coli. |
Purity : | >95% (SDS-PAGE; HPLC). |
Endotoxin Level : | <0.1ng per μg of IL-12p40. |
Stabilizer : | None. |
Formulation : | Lyophilized. |
Biologically Activity : | Test in progress. |
Reconstitution : | The murine IL-12p40 should be reconstituted in water to a concentration of 0.1-1.0mg/ml. This solution can be diluted in water or other buffer solutions or stored at -20°C. |
Stability : | The lyophilized protein is stable for a few weeks at room temperature, but best stored at -20°C. Reconstituted murine IL12p40 should be stored in working aliquots at -20°C. Avoid repeated freeze-thaw cycles. |
Gene Name : | Il12b interleukin 12b [ Mus musculus ] |
Synonyms : | Il12b; interleukin 12b; p40; Il-12b; Il12p40; Il-12p40; IL-12 p40; IL-23 subunit p40; OTTMUSP00000005619 |
Gene ID : | 16160 |
mRNA Refseq : | NM_008352 |
Protein Refseq : | NP_032378 |
UniProt ID : | P43432 |
Chromosome Location : | 11 |
Pathway : | Allograft rejection; Cytokine-cytokine receptor interaction; Jak-STAT signaling pathway; RIG-I-like receptor signaling pathway; Toll-like receptor signaling pathway; Type I diabetes mellitus |
Function : | cytokine activity; cytokine receptor activity; interleukin-12 alpha subunit binding; protein homodimerization activity |
Products Types
◆ Recombinant Protein | ||
IL12B-502H | Recombinant Human IL12B Protein | +Inquiry |
IL12B-2290H | Recombinant Human IL12B Protein, His-tagged | +Inquiry |
IL12B-1164H | Recombinant Human IL12B Protein, His (Fc)-Avi-tagged | +Inquiry |
Il12b-48M | Active Recombinant Mouse Il12b Protein (Met23-Ser335), C-His tagged, Animal-free, Carrier-free | +Inquiry |
IL12B-1001C | Recombinant Chicken IL12B Protein, His-tagged | +Inquiry |
◆ Lysates | ||
IL12B-1000MCL | Recombinant Marmoset IL12B cell lysate | +Inquiry |
IL12B-1101MCL | Recombinant Mouse IL12B cell lysate | +Inquiry |
IL12B-1197RCL | Recombinant Rat IL12B cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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