"BMX" Related Products


Recombinant Human BMX, GST-tagged, Active

Cat. No.: BMX-251H
Product Overview: Recombinant full-length human BMX was expressed by baculovirus inSf9 insect cellsusing a N-terminal GST tag. MW = 110 kDa.
Description: The BMX gene encodes a non-receptor tyrosine kinase, which may play a role in the growth and differentiation of hematopoietic cells. The BMX gene is located on chromosomal band Xp22.2 between the DXS197 and DXS207 loci. Interestingly, chromosome X also contains the closest relative of BMX, the BTK gene, implicated in X-linked agammaglobulinemia. BMX, is found to induce activation of the Stat signaling pathway.
Source: Sf9 insect cells using baculovirus.
Sequence: Full-length.
Applications: Kinase Assay, Western Blot.
Storage And Stability: Store product at –70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
Gene Name: BMX BMX non-receptor tyrosine kinase [ Homo sapiens ]
Synonyms: BMX non-receptor tyrosine kinase; ETK; PSCTK2; PSCTK3; BMX; OTTHUMP00000022965; NTK38 tyrosine kinase; Etk/Bmx cytosolic tyrosine kinase; cytoplasmic tyrosine-protein kinase BMX; EC; NTK38; OTTHUMP00000022964; OTTHUMP00000022966; Epithelial and endothelial tyrosine kinase; Bone marrow tyrosine kinase gene in chromosome X protein
Gene ID: 660
mRNA Refseq: NM_001721
Protein Refseq: NP_001712
MIM: 300101
UniProt ID: P51813
Chromosome Location: Xp22.2
Pathway: Apoptosis
Function: non-membrane spanning protein tyrosine kinase activity; ATP binding; metal ion binding; nucleotide binding; protein binding; signal transducer activity; transferase activity; zinc ion binding

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Optional requirements on this protein    +Expand
C-fusion    N-fusion   Non-tagged
His    GST   Fc   Others
<1.0 eu/μg    <0.1 eu/μg   <0.01 eu/μg   Not required
Monomer Isolation    Dimer Isolation    Not required
>80% by SDS-PAGE    >90% by SDS-PAGE   >95% by SDS-PAGE   Others

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