Recombinant Human BMX Protein, GST-tagged

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Recombinant Human BMX Protein, GST-tagged

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Cat.No. : BMX-290H
Product Overview : Human BMX partial ORF ( AAH16652, 150 a.a. - 280 a.a.) recombinant protein with GST-tag at N-terminal.
Description : This gene encodes a non-receptor tyrosine kinase belonging to the Tec kinase family. The protein contains a PH-like domain, which mediates membrane targeting by binding to phosphatidylinositol 3,4,5-triphosphate (PIP3), and a SH2 domain that binds to tyrosine-phosphorylated proteins and functions in signal transduction. The protein is implicated in several signal transduction pathways including the Stat pathway, and regulates differentiation and tumorigenicity of several types of cancer cells. Multiple alternatively spliced variants, encoding the same protein, have been identified.
Source : Wheat Germ
Species : Human
Tag : GST
Form : 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Molecular Mass : 40.15 kDa
AA Sequence : ANLHTAVNEE KHRVPTFPDR VLKIPRAVPV LKMDAPSSST TLAQYDNESK KNYGSQPPSS STSLAQYDSN SKKIYGSQPN FNMQYIPRED FPDWWQVRKL KSSSSSEDVA SSNQKERNVN HTTSKISWEF P
Quality Control Test : 12.5% SDS-PAGE Stained with Coomassie Blue.
Notes : Best use within three months from the date of receipt of this protein.
Storage : Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
Storage Buffer : 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Figure :

Gene Name : BMX BMX non-receptor tyrosine kinase [ Homo sapiens ]
Official Symbol : BMX
Synonyms : BMX; BMX non-receptor tyrosine kinase; cytoplasmic tyrosine-protein kinase BMX; ETK; PSCTK3; NTK38 tyrosine kinase; Etk/Bmx cytosolic tyrosine kinase; epithelial and endothelial tyrosine kinase; bone marrow tyrosine kinase gene in chromosome X protein; PSCTK2;
Gene ID : 660
mRNA Refseq : NM_001721
Protein Refseq : NP_001712
MIM : 300101
UniProt ID : P51813
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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