Recombinant Human BMX Protein, GST-tagged
Cat.No. : | BMX-290H |
Product Overview : | Human BMX partial ORF ( AAH16652, 150 a.a. - 280 a.a.) recombinant protein with GST-tag at N-terminal. |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes a non-receptor tyrosine kinase belonging to the Tec kinase family. The protein contains a PH-like domain, which mediates membrane targeting by binding to phosphatidylinositol 3,4,5-triphosphate (PIP3), and a SH2 domain that binds to tyrosine-phosphorylated proteins and functions in signal transduction. The protein is implicated in several signal transduction pathways including the Stat pathway, and regulates differentiation and tumorigenicity of several types of cancer cells. Multiple alternatively spliced variants, encoding the same protein, have been identified. |
Source : | Wheat Germ |
Species : | Human |
Tag : | GST |
Form : | 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer. |
Molecular Mass : | 40.15 kDa |
AA Sequence : | ANLHTAVNEEKHRVPTFPDRVLKIP RAVPVLKMDAPSSSTTLAQYDNESK KNYGSQPPSSSTSLAQYDSNSKKIY GSQPNFNMQYIPREDFPDWWQVRKL KSSSSSEDVASSNQKERNVNHTTSK ISWEFP |
Quality Control Test : | 12.5% SDS-PAGE Stained with Coomassie Blue. |
Notes : | Best use within three months from the date of receipt of this protein. |
Storage : | Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing. |
Storage Buffer : | 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer. |
Gene Name : | BMX BMX non-receptor tyrosine kinase [ Homo sapiens ] |
Official Symbol : | BMX |
Synonyms : | BMX; BMX non-receptor tyrosine kinase; cytoplasmic tyrosine-protein kinase BMX; ETK; PSCTK3; NTK38 tyrosine kinase; Etk/Bmx cytosolic tyrosine kinase; epithelial and endothelial tyrosine kinase; bone marrow tyrosine kinase gene in chromosome X protein; PSCTK2; |
Gene ID : | 660 |
mRNA Refseq : | NM_001721 |
Protein Refseq : | NP_001712 |
MIM : | 300101 |
UniProt ID : | P51813 |
Products Types
◆ Recombinant Protein | ||
BMX-0752H | Recombinant Human BMX Protein (E411-H675), His tagged | +Inquiry |
BMX-0751H | Recombinant Human BMX Protein (E411-H675), Tag Free | +Inquiry |
Bmx-716M | Recombinant Mouse Bmx Protein, MYC/DDK-tagged | +Inquiry |
BMX-452H | Recombinant Human BMX Protein, His (Fc)-Avi-tagged | +Inquiry |
BMX-26755TH | Recombinant Human BMX | +Inquiry |
◆ Lysates | ||
BMX-8427HCL | Recombinant Human BMX 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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- Reviews
Q&As (7)
Ask a questionBMX interacts with Tec family kinases to regulate immune cell signaling, affecting immune responses.
Inhibition of BMX reduces angiogenesis in tumor models, suggesting a role in tumor growth and metastasis.
Targeting BMX in cardiovascular diseases offers potential therapeutic benefits, possibly impacting vascular remodeling and function.
BMX kinase substrates vary by cell type, impacting diverse signaling pathways related to cell growth and survival.
BMX expression differs in cancerous tissues, with heightened levels in certain breast and prostate cancers, indicating a potential role in tumor progression.
BMX is involved in regulating inflammatory responses, playing a significant role in autoimmune disease mechanisms.
Phosphorylation alters BMX activity and stability, influencing its function in cellular signaling processes.
Customer Reviews (3)
Write a reviewAccurate mass spectrometry analysis; essential for proteomics research.
Reliable western blot results; a staple for our lab work.
Precise protein quantification; vital for our research projects.
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