"PIM2" Related Products

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Recombinant Human Pim-2 Oncogene, GST-tagged, Active

Cat. No.: PIM2-393H
Product Overview: Recombinant human full-length PIM2 was expressed by baculovirus inSf9 cells usingan N-terminal GST tag. MW=61 kDa.
Description: PIM2 is a serine threonine kinase that is present in all tissues, being most abundant in hematopoietic tissues, spleen, thymus, and peripheral blood leukocytes, as well as in testis, small intestine, and colon. It is highly expressed in human leukemic, lymphoma and colorectal adenocarcinoma cell lines. This suggests a role for PIM2 in proliferating cells as well as during meiosis. Similar to PIM1, PIM2 also acts as a pro-survival kinase and BAD protein is a legitimate PIM2 substrate.
Source: Sf9 insect cells using baculovirus.
Sequence: Full-length.
Applications: Kinase Assay, Western Blot.
Storage And Stability: Store product at –70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
Gene Name: PIM2 pim-2 oncogene [ Homo sapiens ]
Synonyms: PIM2; pim-2 oncogene; PIM; Proto-oncogene serine/threonine-protein kinase Pim-2; EC 2.7.11.1; Pim-2h
Gene ID: 11040
mRNA Refseq: NM_006875
Protein Refseq: NP_006866
UniProt ID: Q9P1W9
Chromosome Location: Xp11.23
MIM: 300295
Pathway: Acute myeloid leukemia
Function: ATP binding; nucleotide binding; transferase activity; protein serine/threonine kinase activity; metal ion binding

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