||Recombinant full length protein (Human)
||The protein encoded by this gene is a polypeptide hormone whose actions appear to be restricted to the nervous system where it promotes neurotransmitter synthesis and neurite outgrowth in certain neuronal populations. The protein is a potent survival factor for neurons and oligodendrocytes and may be relevant in reducing tissue destruction during inflammatory attacks. A mutation in this gene, which results in aberrant splicing, leads to ciliary neurotrophic factor deficiency, but this phenotype is not causally related to neurologic disease. A read-through transcript variant composed of the upstream ZFP91 gene and CNTF sequence has been identified, but it is thought to be non-coding. Read-through transcription of ZFP91 and CNTF has also been observed in mouse.
||Lyophilised:Reconstitute in 5mM Sodium phosphate pH 7.5 to a concentration of 0.1-1 mg/ml
||>95% by SDS-PAGE
||Preservative: NoneConstituents: 5mM Sodium chloride, 5mM Sodium phosphate, pH 7.5
||Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
||Belongs to the CNTF family.